Ichthyosis vulgaris

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Treatments and drugs

By Mayo Clinic staff

There's no known cure for ichthyosis, so the goal of treatment is to manage the condition.

Medications
Treatments may include:

  • Alpha hydroxy acids, such as lactic acid and glycolic acid. Treatment can include prescription creams and ointments that contain acids that help control scaling and increase skin moisture.
  • Retinoids. Your doctor may prescribe these vitamin A-derived medications in severe cases. They reduce the production of skin cells. Side effects from the medication may include eye and lip inflammation, bone spurs and hair loss. Retinoids may cause birth defects. Women considering retinoid therapy should be sure they are not pregnant before starting the medication — and use effective birth control while taking retinoids.
References
  1. Ichthyosis. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/dermatologic_disorders/cornification_disorders/ichthyosis.html#v960749. Accessed Sept. 1, 2012.
  2. Goldstein BG, et al. Metabolic and inherited diseases affecting the skin. http://www.uptodate.com/index. Accessed Sept. 1, 2012.
  3. Ichthyosis vulgaris. Foundation for Ichthyosis & Related Skin Types, Inc. http://www.firstskinfoundation.org/content.cfm/Ichthyosis/Ichthyosis-Vulgaris-Fact-Sheet/page_id/898. Accessed Sept. 1, 2012.
  4. Goldsmith LA, et al., eds. Fitzpatrick's Dermatology in General Medicine. 8th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/content.aspx?aID=56035110. Accessed September 1, 2012.
  5. Okulicz JF, et al. Hereditary and acquired ichthyosis vulgaris. International Journal of Dermatology 2003;42:95.
DS00734 Oct. 20, 2012

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