Idiopathic thrombocytopenic purpura (ITP)

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Symptoms

By Mayo Clinic staff

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Photograph of petechiae on leg and abdomen 
Petechiae

Idiopathic thrombocytopenic purpura (ITP) may have no symptoms. When signs and symptoms do occur, they may include:

  • Easy or excessive bruising (purpura) — your skin naturally bruises and bleeds more easily as you age, but this shouldn't be confused with ITP
  • Superficial bleeding into your skin that appears as a rash of pinpoint-sized reddish-purple spots (petechiae), usually on your lower legs
  • Prolonged bleeding from cuts
  • Spontaneous bleeding from nose
  • Bleeding gums, especially after dental work
  • Blood in urine or stools
  • Unusually heavy menstrual flow
  • Fatigue

When to see a doctor
If you or your child has abnormal bleeding or bruising, or develops a rash of pinpoint-sized red spots, see your doctor. It's also important to seek medical advice if you're a woman who suddenly develops significantly increased menstrual bleeding, as this may be a sign of ITP.

Serious or widespread bleeding indicates an emergency and requires immediate care.

References
  1. What is idiopathic thrombocytopenic purpura? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/itp/printall-index.html. Accessed Feb. 25, 2013.
  2. Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed Feb. 25, 2013.
  3. Tintinalli JE, et al. Tintinalli's Emergency Medicine: A Comprehensive Study Guide. 7th ed. New York, N.Y.: The McGraw Hill Companies; 2011. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=40. Accessed Feb. 25, 2013.
  4. Stone CK, et al. Current Diagnosis & Treatment Emergency Medicine. 7th ed. New York, N.Y.: The McGraw Hill Companies; 2011. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=718. Accessed Feb. 25, 2013.
  5. Guide to understanding ITP (immune thrombocytopenia). ITP Foundation. http://www.itpfoundation.org/itpdefined.htm. Accessed Feb. 25, 2013.
  6. Arnold DM. Positioning new treatments in the management of immune thrombocytopenia. Pediatric Blood & Cancer. 2013;60:S19.
  7. Idiopathic thrombocytopenic purpura (ITP). The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/print/hematology_and_oncology/thrombocytopenia_and_platelet_dysfunction/immune_thrombocytopenic_purpura_itp.html. Accessed Feb. 25, 2013.
  8. Bussel JB. Traditional and new approaches to the management of immune thrombocytopenia: Issues of when and who to treat. Hematology/Oncology Clinics of North America. 2009;23:1329.
DS00844 April 23, 2013

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