IgA nephropathy (Berger's disease)

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Risk factors

By Mayo Clinic staff

Although the exact cause of IgA nephropathy is unknown, some factors may increase your risk of developing this condition:

  • Age. IgA nephropathy can affect people of all ages, including children, but it's most likely to first occur in people in their teens and 20s.
  • Your sex. In North America and western Europe, IgA nephropathy affects at least twice as many men as it does women.
  • Ethnicity. IgA nephropathy is more common in Caucasians and Asians than it is in blacks.
  • Family history. In some cases, IgA nephropathy appears to run in families, indicating that genetic factors may contribute to the disease.
Complications Causes
References
  1. IgA nephropathy. National Institute of Diabetes and Digestive and Kidney Diseases. http://kidney.niddk.nih.gov/kudiseases/pubs/iganephropathy/. Accessed Sept. 21, 2010.
  2. Nephrotic syndrome. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec17/ch235/ch235b.html. Accessed Sept. 22, 2010.
  3. Barrat J, et al. Clinical presentation and diagnosis of IgA nephropathy. http://www.uptodate.com/home/index.html. Accessed Sept. 15, 2010.
  4. Barrat J, et al. Pathogenesis of IgA nephropathy. http://www.uptodate.com/home/index.html. Accessed Sept. 15, 2010.
  5. Donadio JV, et al. IgA nephropathy. The New England Journal of Medicine. 2002;347:738.
  6. Cattran DC, et al. Treatment and prognosis of IgA nephropathy. http://www.uptodate.com/home/index.html. Accessed Sept. 15, 2010.
  7. Cheng J, et al. Efficacy and safety of glucocorticoids therapy for IgA nephropathy: A meta-analysis of randomized controlled trials. American Journal of Nephrology. 2009;30:315.
  8. IgA nephropathy. National Kidney Foundation. http://www.kidney.org/atoz/content/iganeph.cfm. Accessed Sept. 22, 2010.
  9. Anderson CF (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 23, 2010.
DS00856 Nov. 13, 2010

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