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Risk factors
By Mayo Clinic staffAlthough the exact cause of IgA nephropathy is unknown, some factors may increase your risk of developing this condition:
- Age. IgA nephropathy can affect people of all ages, including children, but it's most likely to first occur in people in their teens and 20s.
- Your sex. In North America and western Europe, IgA nephropathy affects at least twice as many men as it does women.
- Ethnicity. IgA nephropathy is more common in Caucasians and Asians than it is in blacks.
- Family history. In some cases, IgA nephropathy appears to run in families, indicating that genetic factors may contribute to the disease.
References
- IgA nephropathy. National Institute of Diabetes and Digestive and Kidney Diseases. http://kidney.niddk.nih.gov/kudiseases/pubs/iganephropathy/. Accessed Sept. 21, 2010.
- Nephrotic syndrome. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec17/ch235/ch235b.html. Accessed Sept. 22, 2010.
- Barrat J, et al. Clinical presentation and diagnosis of IgA nephropathy. http://www.uptodate.com/home/index.html. Accessed Sept. 15, 2010.
- Barrat J, et al. Pathogenesis of IgA nephropathy. http://www.uptodate.com/home/index.html. Accessed Sept. 15, 2010.
- Donadio JV, et al. IgA nephropathy. The New England Journal of Medicine. 2002;347:738.
- Cattran DC, et al. Treatment and prognosis of IgA nephropathy. http://www.uptodate.com/home/index.html. Accessed Sept. 15, 2010.
- Cheng J, et al. Efficacy and safety of glucocorticoids therapy for IgA nephropathy: A meta-analysis of randomized controlled trials. American Journal of Nephrology. 2009;30:315.
- IgA nephropathy. National Kidney Foundation. http://www.kidney.org/atoz/content/iganeph.cfm. Accessed Sept. 22, 2010.
- Anderson CF (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 23, 2010.
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