Infant acid reflux

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Causes

By Mayo Clinic staff

The causes of infant acid reflux are generally simple. Normally, the ring of muscle between the esophagus and the stomach (lower esophageal sphincter) relaxes and opens only when you swallow. Otherwise, it's tightly closed — keeping stomach contents where they belong. Until this muscle matures, stomach contents may sometimes flow up the esophagus and out of your baby's mouth. Sometimes air bubbles in the esophagus may push liquid out of your baby's mouth. In other cases, your baby may simply drink too much, too fast.

References
  1. Tighe MP, et al. Managing gastro-oesophageal reflux in infancy. Archives of Disease in Childhood. 2010;95:243.
  2. Gastroesophageal reflux in infants. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/gerdinfant/gerdinfant.pdf. Accessed June 22, 2010.
  3. Winter HS. Gastroesophageal reflux in infants. http://www.uptodate.com/home/index.html. Accessed June 22, 2010.
  4. Vandenplas Y, et al. Pediatric gastroesophageal reflux clinical practice guidelines: Joint recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN). Journal of Pediatric Gastroenterology and Nutrition. 2009;49:498.
  5. Sondheimer JM, et al. Gastrointestinal tract. In: Hay WW, et al. Current Diagnosis & Treatment: Pediatrics. 19th ed. New York, N.Y.; McGraw-Hill: 2009. http://www.accessmedicine.com/content.aspx?aID=3403837. Accessed June 18, 2010.
  6. Hoecker JL (expert opinion). Mayo Clinic, Rochester, Minn. June 24, 2010.
  7. FDA Drug Safety Communication: Possible increased risk of fractures of the hip, wrist and spine with the use of proton pump inhibitors. Food and Drug Administration. http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm213206.htm. Accessed August 4, 2010.
DS00787 Aug. 21, 2010

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