Free
E-newsletter
Subscribe to Housecall
Our weekly general interest
e-newsletter keeps you up to date
on a wide variety of health topics.
close window
Mayo Clinic Housecall
Stay up to date on the latest health information.
What you get
- Free weekly e-newsletter
- Mayo Clinic expertise
- Recipes, tools and other helpful information
- We do not share your e-mail address
Treatments and drugs
By Mayo Clinic staffMild infant jaundice often disappears on its own within two or three weeks. If your baby has moderate or severe jaundice, he or she may need to stay longer in the newborn nursery or be readmitted to the hospital.
Treatments to lower the level of bilirubin in your baby's blood may include:
- Light therapy (phototherapy). Your baby may be placed under special lighting that emits light in the blue-green spectrum. The light changes the shape and structure of bilirubin molecules in such a way that they can be excreted in the urine and stool. The light isn't an ultraviolet light, and a protective plastic shield filters out any ultraviolet light that may be emitted. During the treatment, your baby will wear only a diaper and protective eye patches. The light therapy may be supplemented with the use of a light-emitting pad or mattress.
- Intravenous immunoglobulin (IVIg). Jaundice may be related to blood type differences between mother and baby. This condition results in the baby carrying antibodies from the mother that contribute to the breakdown of blood cells in the baby. Intravenous transfusion of immunoglobulin, a blood protein that can reduce levels of antibodies, may decrease jaundice and lessen the need for an exchange blood transfusion.
- Exchange blood transfusion. Rarely, when severe jaundice doesn't respond to other treatments, a baby may need an exchange transfusion of blood. This involves repeatedly withdrawing small amounts of blood, diluting the bilirubin and maternal antibodies, and then transferring blood back into the baby — a procedure that's performed in a newborn intensive care unit.
References
- Jaundice. American Academy of Pediatrics. http://www.healthychildren.org/English/ages-stages/baby/Pages/Jaundice.aspx. Accessed Feb. 24, 2011.
- Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. American Academy of Pediatrics Policy. http://aappolicy.aappublications.org/cgi/content/full/pediatrics;114/1/297. Accessed Feb. 24, 2011.
- Neonatal hyperbilirubinemia. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/sec19/ch274/ch274b.html?qt=neonatal%20hyperbilirubinemia&alt=sh. Accessed Feb. 24, 2011.
- Lease M, et al. Assessing jaundice in infants of 35-week gestation and greater. Current Opinion in Pediatrics. 2010;22:352.
- Cohen RS, et al. Understanding neonatal jaundice: A perspective on causation. Pediatric Neonatology. 2010;51:143.
- Wong RJ, et al. Treatment of unconjugated hyperbilirubinemia in term and late preterm infants. http://www.uptodate.com/home/index.html. Accessed Feb. 24, 2011.
- Moerschel SK, et al. A practical approach to neonatal jaundice. American Family Physician. 2008;77:1255.
Find Mayo Clinic on