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Causes

By Mayo Clinic staff

Infectious diseases can be caused by:

  • Bacteria. These one-cell organisms are responsible for illnesses such as strep throat, urinary tract infections and tuberculosis.
  • Viruses. Even smaller than bacteria, viruses cause a multitude of diseases — ranging from the common cold to AIDS.
  • Fungi. Many skin diseases, such as ringworm and athlete's foot, are caused by fungi. Other types of fungi can infect your lungs or nervous system.
  • Parasites. Malaria is caused by a tiny parasite that is transmitted by a mosquito bite. Other parasites may be transmitted to humans from animal feces.

Direct contact
An easy way to catch most infectious diseases is by coming in contact with a person or animal who has the infection.Three ways infectious diseases can be spread through direct contact are:

  • Person to person. The most common way for infectious diseases to spread is through the direct transfer of bacteria, viruses or other germs from one person to another. This can occur when an individual with the bacterium or virus touches, coughs on or kisses someone who isn't infected. These germs can also spread through the exchange of body fluids from sexual contact or a blood transfusion. The person who passes the germ may have no symptoms of the disease, but may simply be a carrier.
  • Animal to person. Pets can carry many germs. Being bitten or scratched by an infected animal can make you sick and, in extreme circumstances, can be fatal. Handling animal waste can be hazardous, too. For example, you can acquire a toxoplasmosis infection by scooping your cat's litter box.
  • Mother to unborn child. A pregnant woman may pass germs that cause infectious diseases to her unborn baby. Some germs can pass through the placenta. Germs in the vagina can be transmitted to the baby during birth.

Indirect contact
Disease-causing organisms also can be passed by indirect contact. Many germs can linger on an inanimate object, such as a tabletop, doorknob or faucet handle. When you touch a doorknob handled by someone ill with the flu or a cold, for example, you can pick up the germs he or she left behind. If you then touch your eyes, mouth or nose before washing your hands, you may become infected.

Insect bites
Some germs rely on insect carriers — such as mosquitoes, fleas, lice or ticks — to move from host to host. These carriers are known as vectors. Mosquitoes can carry the malaria parasite or West Nile virus, and deer ticks may carry the bacterium that causes Lyme disease.

Food contamination
Another way disease-causing germs can infect you is through contaminated food and water. This mechanism of transmission allows germs to be spread to many people through a single source. E. coli, for example, is a bacterium present in or on certain foods — such as undercooked hamburger or unwashed fruits or vegetables.

References
  1. Understanding microbes in sickness and in health. National Institute of Allergy and Infectious Diseases. http://www.niaid.nih.gov/topics/microbes/documents/microbesbook.pdf. Accessed Oct. 8, 2012.
  2. Long SS, et al. Long: Principles and Practice of Pediatric Infectious Diseases. 4th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-1-4377-2702-9..C2009-0-41480-6--TOP&isbn=978-1-4377-2702-9&uniqId=372964036-9. Accessed Oct. 8, 2012.
  3. Facts about infectious diseases. Infectious Diseases Society of America. http://www.idsociety.org/Facts_About_ID/#. Accessed Oct. 8, 2012.
  4. Escherichia coli infections. World Health Organization. http://www.emro.who.int/health-topics/escherichia-coli-infections/. Accessed Oct. 10, 2012.
  5. De Martel C, et al. Global burden of cancers attributable to infections in 2008: A review and synthetic analysis. The Lancet Oncology. 2012;13:607.
  6. Personal prevention of MRSA skin infections. Centers for Disease Control and Prevention. http://www.cdc.gov/mrsa/prevent/personal.html. Accessed Oct. 10, 2012.
  7. Sexually transmitted diseases (STDs). Centers for Disease Control and Prevention. http://www.cdc.gov/std/treatment/2006/clinical.htm. Accessed Oct. 10, 2012.
DS01145 Jan. 23, 2013

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