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By Mayo Clinic staffUsually, you'll need nothing more than bed rest and plenty of fluids to treat the flu. But in some cases, your doctor may prescribe an antiviral medication such as oseltamivir (Tamiflu) or zanamivir (Relenza).
These drugs, which treat both influenza A and B, work by deactivating an enzyme the virus needs to grow and spread. If taken soon after you notice symptoms, they may shorten your illness by a day or so. Oseltamivir is an oral medication, but zanamivir is inhaled through a device similar to an asthma inhaler and shouldn't be used by anyone with respiratory conditions, such as asthma and lung disease.
Both medications can cause side effects, including lightheadedness, nausea, vomiting, loss of appetite and trouble breathing. They can also lead to the development of antiviral-resistant viruses.
In November 2006, the Food and Drug Administration (FDA) required the maker of Tamiflu to include a warning that people with the flu, particularly children, may be at increased risk of self-injury and confusion after taking Tamiflu. The FDA recommends that individuals with the flu who take Tamiflu be closely monitored for signs of unusual behavior. Discuss possible side effects with your doctor before starting any antiviral medication.