Risk factorsBy Mayo Clinic staff
Your risk of developing iritis increases if you:
- Have a specific genetic alteration. People with HLA-B27, a specific change in a gene that's essential for healthy immune system function, are more likely to develop iritis.
- Develop a sexually transmitted infection (STI), because infections such as syphilis or human immunodeficiency virus (HIV) are linked with a significantly increased risk of iritis.
- Live in certain geographic locations where infectious causes are more prevalent, for instance, in the U.S. in the Ohio or Mississippi river valleys where histoplasmosis — a fungal infection — occurs more frequently.
- Have a compromised immune system or autoimmune disorder.
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