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Treatments and drugs

By Mayo Clinic staff

To treat iron deficiency anemia, your doctor may recommend you take iron supplements. Your doctor will also treat the underlying cause of your iron deficiency, if necessary.

Iron supplements
Your doctor may recommend iron tablets to replenish the iron stores in your body. To improve the chances that your body will absorb the iron in the tablets, you may be instructed to:

  • Take iron tablets on an empty stomach. If possible, take your iron tablets when your stomach is empty. However, because iron tablets can upset your stomach, you may need to take your iron tablets with meals.
  • Take iron tablets with vitamin C. Vitamin C improves the absorption of iron. Your doctor might recommend taking your iron tablets with a glass of orange juice or with a vitamin C supplement.

Iron supplements can cause constipation, so your doctor may also recommend a stool softener. Iron may turn your stools black, which is a harmless side effect.

Iron deficiency can't be corrected overnight. You may need to take iron supplements for several months or longer to replenish your iron reserves. Generally, you'll start to feel better after a week or so of treatment. Ask your doctor when you need to return to have your blood rechecked to measure your iron levels.

Treating underlying causes of iron deficiency
If iron supplements don't increase your blood-iron levels, it's likely the anemia is due to a source of bleeding or an iron-absorption problem that your doctor will need to investigate and treat. Depending on the cause, iron deficiency anemia treatment may involve:

  • Medications, such as oral contraceptives to lighten heavy menstrual flow
  • Antibiotics and other medications to treat peptic ulcers
  • Surgery to remove a bleeding polyp, a tumor or a fibroid

If iron deficiency anemia is severe, blood transfusions can help replace iron and hemoglobin quickly.

References
  1. Brittenham GM. Disorders of iron metabolism: Iron deficiency and iron overload. In: Hoffman R, et al. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2009. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-443-06715-0..X5001-8--TOP&isbn=978-0-443-06715-0&uniqId=230100505-56. Accessed Jan. 24, 2011.
  2. Iron-deficiency anemia. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/ida/ida_all.html. Accessed Jan. 24, 2011.
  3. Iron-deficiency anemia. American Society of Hematology. http://www.hematology.org/Patients/Blood-Disorders/Anemia/5263.aspx. Accessed Jan. 24, 2011.
  4. Laboratory reference values. Hematology group. Rochester, Minn.: Mayo Foundation for Medical Education and Research; January 2011.
  5. Reiss RF, et al. Current concerns for blood donor well-being and health. Southern Medical Journal. 2010;103:343.
DS00323 March 4, 2011

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