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Housecall, our weekly general-interest e-newsletter, keeps you up to date on a wide variety of health topics with timely, reliable, practical information, recipes, blogs, questions and answers with Mayo Clinic experts and more. Our biweekly topic-specific e-newsletters also include blogs, questions and answers with Mayo Clinic experts, and other useful information that will help you manage your health.
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Causes
By Mayo Clinic staffJuvenile rheumatoid arthritis occurs when the body's immune system attacks its own cells and tissues. It's unknown why this happens, but both heredity and environment seem to play a role. Certain gene mutations may make a person more susceptible to environmental factors — such as viruses — that may trigger the disease.
References
- Questions and answers about juvenile arthritis. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Juv_Arthritis/default.asp. Accessed Aug. 24, 2011.
- Wu EY, et al. Juvenile idiopathic arthritis. In: Kliegman RM, et al. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/208746819-6/0/1608/0.html. Accessed Aug. 24, 2011.
- Arthritis in children. American College of Rheumatology. http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/juvenilearthritis.asp. Accessed Aug. 24, 2011.
- Juvenile arthritis. American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=a00075. Accessed Aug. 25, 2011.
- Mason TG (expert opinion). Mayo Clinic, Rochester, Minn. Aug. 26, 2011.
- Lehman TJ. Polyarticular onset juvenile idiopathic arthritis: Management. http://www.uptodate.com/home/index.html. Accessed Aug. 25, 2011.
- What is life with juvenile arthritis like? Arthritis Foundation. http://www.arthritis.org/life-with-juvenile-arthritis.php. Accessed Aug. 25, 2011.
- Juvenile Arthritis Alliance. Arthritis Foundation. http://www.arthritis.org/juvenile-arthritis-alliance.php. Accessed Aug. 25, 2011.
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