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Symptoms

By Mayo Clinic staff

Kawasaki disease symptoms appear in phases.

First phase
Signs and symptoms of the first phase may include:

  • Fever, which often is higher than 101.3 F (38.5 C) and lasts one to two weeks
  • Extremely red eyes (conjunctivitis) without a thick discharge
  • A rash on the main part of the body (trunk) and in the genital area
  • Red, dry, cracked lips and an extremely red, swollen tongue ("strawberry" tongue)
  • Swollen, red skin on the palms of the hands and the soles of the feet
  • Swollen lymph nodes in the neck and perhaps elsewhere
  • Irritability

Second phase
In the second phase of the disease, your child may develop:

  • Peeling of the skin on the hands and feet, especially the tips of the fingers and toes, often in large sheets
  • Joint pain
  • Diarrhea
  • Vomiting
  • Abdominal pain

Third phase
In the third phase of the disease, signs and symptoms slowly go away unless complications develop. It may be as long as eight weeks before energy levels seem normal again.

When to see a doctor
If your child has a fever that lasts more than four days, contact your child's doctor. Or, see your child's doctor if your child has a fever along with four or more of the following signs and symptoms:

  • Redness in both eyes
  • A very red, swollen tongue
  • Redness of the palms or soles
  • Skin peeling
  • A rash
  • Swollen lymph nodes

Treating Kawasaki disease within 10 days of its onset may greatly reduce the chances of lasting damage.

References
  1. Kawasaki disease. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/sec19/ch286/ch286d.html#sec19-ch286-ch286c-1987. Accessed Dec. 7, 2010.
  2. Harnden A, et al. Kawasaki disease. British Medical Journal. 2009;338:1514.
  3. Baker AL, et al. Kawasaki disease. Circulation. 2008;118:e110.
  4. Wood LE, et al. Kawasaki disease in children. Heart. 2009;95:787.
  5. Kawasaki Disease. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=4634. Accessed Oct. 25, 2010.
  6. Sundel R. Initial treatment and prognosis of Kawasaki disease. http://www.uptodate.com/home/index.html. Accessed Dec. 1, 2010.
DS00576 Jan. 28, 2011

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