Keratosis pilaris

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Treatments and drugs

By Mayo Clinic staff

No single treatment universally improves keratosis pilaris. But most options, including self-care measures and medicated creams, focus on softening the keratin deposits in the skin.

Treatment of keratosis pilaris can include the following prescription medications:

  • Ammonium lactate (Lac-Hydrin). Available in a cream or lotion, 12 percent ammonium lactate reduces roughness and softens the keratin plugs. It won't, however, lessen the redness caused by the condition.
  • Urea (Carmol, Keralac). Urea moisturizes and softens dry, rough skin. It also helps loosen and remove the dead skin cells. Side effects include redness, stinging and skin irritations.
  • Topical corticosteroids. These anti-inflammatory drugs help decrease cell turnover by suppressing the immune system. Low-potency corticosteroid ointments are usually recommended for sensitive areas such as your face and for treating widespread patches. Doctors usually prescribe corticosteroids for short-term treatment or for temporary relief of symptoms. They aren't used as long-term treatments because of potential side effects.
  • Topical retinoids. Derived from vitamin A, retinoids work by promoting cell turnover and preventing the plugging of the hair follicle. Retinoids may be an effective treatment, but they can cause bothersome skin irritations, such as severe dryness, redness and peeling. Tretinoin (Retin-A Micro, Avita) and tazarotene (Tazorac) are examples of topical retinoids.

Using a medication regularly may improve the appearance of your skin. But if you stop, the condition returns. And even with medical treatment, keratosis pilaris tends to persist for years.

DS00769

July 11, 2008

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