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Definition

By Mayo Clinic staff

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Illustration showing kidney biopsy 
Kidney biopsy

A kidney biopsy, also called renal biopsy, is a procedure to remove a small piece of kidney tissue so that it can be examined under a microscope for signs of damage or disease. Your doctor may recommend a kidney biopsy if blood tests, urine tests or imaging techniques don't provide enough information to diagnose a kidney problem. A kidney biopsy may also be used to determine the severity of kidney disease or to find out if treatment for kidney disease is working. You may need a kidney biopsy if you've had a kidney transplant that's not working properly.

Most kidney biopsies are performed by inserting a thin needle through the skin. In this procedure, an imaging device helps guide the needle into one of your kidneys to remove tissue.

References
  1. Kidney biopsy. National Institute of Diabetes and Digestive and Kidney Diseases. kidney.niddk.nih.gov/Kudiseases/pubs/pdf/KidneyBiopsy.pdf. Accessed March 1, 2010.
  2. Whittier WL, et al. Indications for and complications of renal biopsy. http://www.uptodate.com/home/index.html. Accessed March 1, 2010.
  3. Walker PL. The renal biopsy. Archives of Pathology and Laboratory Medicine. 2009;133:181.
  4. Kidney biopsy: A guide for patients. National Kidney Foundation. http://www.kidney.org/atoz/atozcopy.cfm?pdflink=11-10-0106_PatBro_RenalBiopsy.pdf. Accessed March 1, 2010.
  5. Brenner BM. Kidney biopsy. In: Brenner BM. Brenner and Rector's The Kidney. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-1-4160-3105-5..50025-6--cesec44&uniq=191360963&isbn=978-1-4160-3105-5&sid=974056109. Accessed March 1, 2010.
  6. Watnick S, et al. Kidney disease. In: McPhee SJ, et al. Current Medical Diagnosis & Treatment 2010. http://www.accessmedicine.com/content.aspx?aID=11374. Accessed March 1, 2010.
MY01223 April 13, 2010

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