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  • With Mayo Clinic urologist

    Erik Castle, M.D.

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Mayo Clinic Health Manager

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Question

Kidney donation: Are there long-term risks?

I'm considering kidney donation. Are there long-term risks?

Answer

from Erik Castle, M.D.

Research has shown that there's little long-term risk of kidney donation, provided you're carefully screened before becoming a donor. As a potential kidney donor, you'll receive a thorough medical exam to determine whether you're a good match for the potential recipient. And you'll be carefully checked to make sure you don't have any health problems that might be made worse by donating a kidney.

Kidney donation involves major surgery, and there are risks including bleeding and infection. After your kidney is removed (nephrectomy), you'll spend time recovering in the hospital and at home. With time, your remaining kidney will enlarge as it takes on additional blood flow and filtration of wastes.

Your long-term survival rate, quality of life, general health status and risk of kidney failure are about the same as that for people in the general population who aren't kidney donors. Regular checkups, including monitoring of your kidney function and blood pressure, are necessary to evaluate your health after kidney donation.

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References
  1. Ibrahim HN, et al. Long-term consequences of kidney donation. New England Journal of Medicine. 2009;360:459.
  2. Tan JC, et al. Cautious optimism concerning long-term safety of kidney donation. New England Journal of Medicine. 2009;360:522.
  3. Carpenter CB, et al. Transplantation in the treatment of renal failure. In: Fauci AS, et al. Harrison's Principles of Internal Medicine. 17th ed. New York, N.Y.: McGraw Hill; 2008. Accessed May 7, 2009.
  4. Treatment measures for kidney failure: Transplantation. National Institute of Diabetes and Digestive and Kidney Diseases. Accessed May 7, 2009.
  5. Berge KG (expert opinion). Mayo Clinic, Rochester, Minn. May 11, 2009.

AN01988

May 23, 2009

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