Free
E-newsletter
Subscribe to Housecall
Our weekly general interest
e-newsletter keeps you up to date
on a wide variety of health topics.
Mayo Clinic Housecall
Stay up to date on the latest health information.
What you get
- Free weekly e-newsletter
- Mayo Clinic expertise
- Recipes, tools and other helpful information
- We do not share your e-mail address
Definition
By Mayo Clinic staff
Chronic kidney failure, also called chronic kidney disease, describes the gradual loss of kidney function. Your kidneys filter wastes and excess fluids from your blood, which are then excreted in your urine. When chronic kidney failure reaches an advanced stage, dangerous levels of fluid, electrolytes and wastes can accumulate in your body.
In the early stages of chronic kidney failure, you may have few signs or symptoms. Chronic kidney failure may not become apparent until your kidney function is significantly impaired.
Treatment for chronic kidney failure focuses on slowing the progression of the kidney damage, usually by controlling the underlying cause. Chronic kidney failure can progress to end-stage kidney disease, which is fatal without artificial filtering (dialysis) or a kidney transplant.
- Goldman L, et al. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed April 2, 2012.
- Ferri FF. Ferri's Clinical Advisor 2012: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-323-05611-3..C2009-0-38601-8--TOP&isbn=978-0-323-05611-3&uniqId=291436269-101. Accessed April 2, 2012.
- Marx JA, et al. Rosen's Emergency Medicine: Concepts and Clinical Practice. 7th ed. Philadelphia, Pa.: Mosby Elsevier; 2010. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-323-05472-0..X0001-1--TOP&isbn=978-0-323-05472-0&uniqId=230100505-57. Accessed April 2, 2012.
- Bope ET, et al. Conn's Current Therapy. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4377-0986-5..C2009-0-38984-9--TOP&isbn=978-1-4377-0986-5&about=true&uniqId=236797353-5. Accessed April 3, 2012.
- About chronic kidney disease: A guide for patients and their families. National Kidney Foundation. http://www.kidney.org/atoz/content/aboutckd.cfm. Accessed April 3, 2012.
- Coping effectively: A guide to living well with kidney failure. National Kidney Foundation. http://www.kidney.org/atoz/pdf/coping.pdf. Accessed April 3, 2012.
- Kidney failure: Choosing a treatment that's right for you. National Kidney & Urologic Diseases Information Clearinghouse. http://kidney.niddk.nih.gov/KUDiseases/pubs/choosingtreatment/index.aspx. Accessed April 2, 2012.
- Chronic kidney disease stage 5: Nutrition guidelines. Nutrition Care Manual. American Dietetic Association. http://nutritioncaremanual.org/index.cfm. Accessed April 3, 2012.
- The kidneys and how they work. National Kidney & Urologic Diseases Information Clearinghouse. http://kidney.niddk.nih.gov/kudiseases/pubs/yourkidneys/. Accessed April 4, 2012.
- El-Zoghby ZM (expert opinion). Mayo Clinic, Rochester, Minn. May 1, 2012.
- Anderson CF (expert opinion). Mayo Clinic, Rochester, Minn. April 24, 2012.
- Rethinking drinking: Alcohol and your health. National Institute on Alcohol Abuse and Alcoholism. http://pubs.niaaa.nih.gov/publications/RethinkingDrinking/Rethinking_Drinking.pdf. Accessed May 8, 2012.
- Dietary guidelines for Americans, 2010. U.S. Department of Health and Human Services. http://www.cnpp.usda.gov/DGAs2010-PolicyDocument.htm. Accessed May 8, 2012.
- Post R (expert opinion). U.S. Department of Agriculture, Alexandria, Va. Aug. 8, 2011.
Find Mayo Clinic on