Complications
By Mayo Clinic staffChronic kidney failure can affect almost every part of your body. Potential complications may include:
- Fluid retention, which could lead to swelling in your arms and legs, high blood pressure or fluid in your lungs (pulmonary edema)
- A sudden rise in potassium levels in your blood (hyperkalemia), which could impair your heart's ability to function and may be life-threatening
- Cardiovascular disease
- Weak bones and an increased risk of bone fractures
- Anemia
- Decreased sex drive or impotence
- Damage to your central nervous system, which can cause difficulty concentrating, personality changes or seizures
- Decreased immune response, which makes you more vulnerable to infection
- Pericarditis, an inflammation of the sac-like membrane that envelops your heart (pericardium)
- Pregnancy complications that carry risks for the mother and the developing fetus
- Irreversible damage to your kidneys (end-stage kidney disease), eventually requiring either dialysis or a kidney transplant for survival
References
- Mitch WE. Chronic kidney disease. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders; 2007. http://www.mdconsult.com/das/book/body/192064788-4/0/1492/0.html. Accessed March 30, 2010.
- Ferri FF. Renal failure, chronic. In: Ferri FF. Ferri's Clinical Advisor 2010. Philadelphia, Pa.: Mosby; 2009. http://www.mdconsult.com/das/book/body/192064788-4/0/2088/0.html. Accessed March 30, 2010.
- Wolfson AB. Renal failure. In: Marx JA, et al. Rosen's Emergency Medicine: Concepts and Clinical Practice. 7th ed. Philadelphia, Pa.: Mosby; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-0-323-05472-0..X0001-1--TOP&isbn=978-0-323-05472-0&uniq=193452254. Accessed March 30, 2010.
- Kraut JA. Chronic renal failure. In: Bope ET, et al. Conn's Current Therapy 2010. Philadelphia, Pa.: Saunders Elsevier; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-1-4160-6642-2..C2009-0-38983-7--TOP&isbn=978-1-4160-6642-2&uniq=192064788. Accessed March 30, 2010.
- About chronic kidney disease: A guide for patients and their families. National Kidney Foundation. http://www.kidney.org/atoz/atozcopy.cfm?pdflink=11-50-0160_JAI_PatBro_AboutCKDv2lr.pdf. Accessed April 5, 2010.
- Coping effectively: A guide for patients and their families. National Kidney Foundation. http://www.kidney.org/atoz/atozcopy.cfm?pdflink=coping.pdf. Accessed April 5, 2010.
- Kidney failure: Choosing a treatment that's right for you. National Institute of Diabetes and Digestive and Kidney Diseases. http://kidney.niddk.nih.gov/kudiseases/pubs/choosingtreatment/index.htm. Accessed March 30, 2010.
- Chronic kidney disease stage 5 nutrition therapy for people not on dialysis. ADA Nutrition Care Manual. http://nutritioncaremanual.org/vault/editor/Docs/ChronicKidneyDiseaseNutritionTherapyNo%20Dialysis_FINAL.pdf. Accessed April 6, 2010.

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