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Symptoms

By Mayo Clinic staff

Signs and symptoms of kidney failure develop slowly over time if kidney damage progresses slowly. Signs and symptoms of kidney failure may include:

  • Decreased urine output or no urine output
  • Nausea
  • Vomiting
  • Loss of appetite
  • Fatigue and weakness
  • Sleep problems
  • Decreased mental sharpness
  • Muscle twitches and cramps
  • Swelling of the feet and ankles
  • Persistent itching

Signs and symptoms of kidney failure are often nonspecific, meaning they can also be attributed to other illnesses. In addition, because your kidneys are highly adaptable and able to compensate for lost function, signs and symptoms of kidney failure may not appear until irreversible damage has occurred.

When to see a doctor
Make an appointment with your doctor if you have any signs or symptoms that worry you.

If you have a chronic medical condition that increases your risk of chronic kidney failure, your doctor is likely to monitor your blood pressure and kidney function with urine and blood tests during regularly scheduled office visits. Ask your doctor whether these types of tests are right for you.

References
  1. Mitch WE. Chronic kidney disease. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders; 2007. http://www.mdconsult.com/das/book/body/192064788-4/0/1492/0.html. Accessed March 30, 2010.
  2. Ferri FF. Renal failure, chronic. In: Ferri FF. Ferri's Clinical Advisor 2010. Philadelphia, Pa.: Mosby; 2009. http://www.mdconsult.com/das/book/body/192064788-4/0/2088/0.html. Accessed March 30, 2010.
  3. Wolfson AB. Renal failure. In: Marx JA, et al. Rosen's Emergency Medicine: Concepts and Clinical Practice. 7th ed. Philadelphia, Pa.: Mosby; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-0-323-05472-0..X0001-1--TOP&isbn=978-0-323-05472-0&uniq=193452254. Accessed March 30, 2010.
  4. Kraut JA. Chronic renal failure. In: Bope ET, et al. Conn's Current Therapy 2010. Philadelphia, Pa.: Saunders Elsevier; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-1-4160-6642-2..C2009-0-38983-7--TOP&isbn=978-1-4160-6642-2&uniq=192064788. Accessed March 30, 2010.
  5. About chronic kidney disease: A guide for patients and their families. National Kidney Foundation. http://www.kidney.org/atoz/atozcopy.cfm?pdflink=11-50-0160_JAI_PatBro_AboutCKDv2lr.pdf. Accessed April 5, 2010.
  6. Coping effectively: A guide for patients and their families. National Kidney Foundation. http://www.kidney.org/atoz/atozcopy.cfm?pdflink=coping.pdf. Accessed April 5, 2010.
  7. Kidney failure: Choosing a treatment that's right for you. National Institute of Diabetes and Digestive and Kidney Diseases. http://kidney.niddk.nih.gov/kudiseases/pubs/choosingtreatment/index.htm. Accessed March 30, 2010.
  8. Chronic kidney disease stage 5 nutrition therapy for people not on dialysis. ADA Nutrition Care Manual. http://nutritioncaremanual.org/vault/editor/Docs/ChronicKidneyDiseaseNutritionTherapyNo%20Dialysis_FINAL.pdf. Accessed April 6, 2010.
DS00682 May 13, 2010

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