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Definition
By Mayo Clinic staff
Chronic kidney failure describes the gradual loss of kidney function. Your kidneys filter wastes and excess fluids from your blood which are then excreted in your urine. When chronic kidney failure damages your kidneys, dangerous levels of fluid and waste can accumulate in your body.
In the early stages of chronic kidney failure, you may have few signs or symptoms. Chronic kidney failure may not become apparent until your kidney function is significantly impaired.
Treatment for chronic kidney failure, also called chronic kidney disease, focuses on slowing the progression of the kidney damage, usually by controlling the underlying cause. Chronic kidney failure can progress to end-stage kidney disease, which is fatal without artificial filtering (dialysis) or a kidney transplant.
- Mitch WE. Chronic kidney disease. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders; 2007. http://www.mdconsult.com/das/book/body/192064788-4/0/1492/0.html. Accessed March 30, 2010.
- Ferri FF. Renal failure, chronic. In: Ferri FF. Ferri's Clinical Advisor 2010. Philadelphia, Pa.: Mosby; 2009. http://www.mdconsult.com/das/book/body/192064788-4/0/2088/0.html. Accessed March 30, 2010.
- Wolfson AB. Renal failure. In: Marx JA, et al. Rosen's Emergency Medicine: Concepts and Clinical Practice. 7th ed. Philadelphia, Pa.: Mosby; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-0-323-05472-0..X0001-1--TOP&isbn=978-0-323-05472-0&uniq=193452254. Accessed March 30, 2010.
- Kraut JA. Chronic renal failure. In: Bope ET, et al. Conn's Current Therapy 2010. Philadelphia, Pa.: Saunders Elsevier; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-1-4160-6642-2..C2009-0-38983-7--TOP&isbn=978-1-4160-6642-2&uniq=192064788. Accessed March 30, 2010.
- About chronic kidney disease: A guide for patients and their families. National Kidney Foundation. http://www.kidney.org/atoz/atozcopy.cfm?pdflink=11-50-0160_JAI_PatBro_AboutCKDv2lr.pdf. Accessed April 5, 2010.
- Coping effectively: A guide for patients and their families. National Kidney Foundation. http://www.kidney.org/atoz/atozcopy.cfm?pdflink=coping.pdf. Accessed April 5, 2010.
- Kidney failure: Choosing a treatment that's right for you. National Institute of Diabetes and Digestive and Kidney Diseases. http://kidney.niddk.nih.gov/kudiseases/pubs/choosingtreatment/index.htm. Accessed March 30, 2010.
- Chronic kidney disease stage 5 nutrition therapy for people not on dialysis. ADA Nutrition Care Manual. http://nutritioncaremanual.org/vault/editor/Docs/ChronicKidneyDiseaseNutritionTherapyNo%20Dialysis_FINAL.pdf. Accessed April 6, 2010.
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