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Causes
By Mayo Clinic staffKlinefelter syndrome occurs when a boy inherits an extra sex chromosome from one of his parents during the formation of the embryo. It's a random occurrence and happens entirely by chance. Unlike other chromosomal disorders such as Down syndrome, having a family history of Klinefelter syndrome, or having an older mother at birth doesn't appear to make a person more likely to have the disorder.
- Klinefelter syndrome. National Institutes of Health. http://www.nichd.nih.gov/health/topics/klinefelter_syndrome.cfm. Accessed Feb. 19, 2008.
- Klinefelter syndrome. Madison's Foundation. http://www.madisonsfoundation.org/index.php/component/option,com_mpower/diseaseID,195/. Accessed Feb. 19, 2008.
- Lanfranko F, et al. Klinefelter's syndrome. The Lancet. 2004;364(9430):273-283
- Bojesen A, et al. Klinefelter syndrome in clinical practice. Nature Clinical Practice Urology. 2007;4(4):192-193.
- Klinefelter syndrome. U.S. National Library of Medicine. http://ghr.nlm.nih.gov/condition=klinefeltersyndrome. Accessed Feb. 26, 2008.
- Klinefelter (XXY) syndrome. California Department of Developmental Services. http://www.ddhealthinfo.org/coursebuilder/?id=25. Accessed Feb. 19, 2008.
