Left ventricular hypertrophy

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Risk factors

By Mayo Clinic staff

Heart-Healthy Living

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Risk factors for left ventricular hypertrophy include the following:

  • High blood pressure, a blood pressure reading greater than 140/90 mm Hg increases your risk of left ventricular hypertrophy. In addition, a nighttime blood pressure reading greater than 120/80 mm Hg also increases your risk.
  • Obesity can cause high blood pressure and increase your body's demand for oxygen, factors that may lead to left ventricular hypertrophy.
  • Aortic stenosis, narrowing of the main valve through which blood leaves the heart, may increase the left ventricle's workload.
  • Certain genes. Certain genes are associated with an increased risk of left ventricular hypertrophy.
References
  1. Douglas PS, et al. Definition and pathogenesis of left ventricular hypertrophy in hypertension. http://www.uptodate.com/index. Accessed May 28, 2012.
  2. Kaplan NM, et al. Clinical implications and treatment of left ventricular hypertrophy in hypertension. http://www.uptodate.com/ index. Accessed May 28, 2012.
  3. Katholi RE, et al. Left ventricular hypertrophy: Major risk factor in patients with hypertension — Update and practical clinical applications. International Journal of Hypertension. 2011;495349:1.
  4. Lorell BH, et al. Left ventricular hypertrophy: Pathogenesis, detection, and prognosis. Circulation. 2000;102:470.
  5. Rawlins J, et al. Left ventricular hypertrophy in athletes. European Journal of Echocardiography. 2009;10:350.
  6. Artham SM, et al. Clinical impact of left ventricular hypertrophy and implications for regression. Progress in Cardiovascular Diseases. 2009;52:153.
  7. What is high blood pressure? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/hbp/. Accessed May 30, 2012.
  8. Aortic valve stenosis (AS) and aortic insufficiency (AI). American Heart Association. http://www.heart.org/HEARTORG/Conditions/CongenitalHeartDefects/AboutCongenitalHeartDefects/Aortic-Valve-Stenosis-AVS_UCM_307020_Article.jsp. Accessed May 30, 2012.
  9. Gersh BJ, et al. 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2011;124:e783.
DS00680 July 18, 2012

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