Brain lesion: What does it mean?

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  • With Mayo Clinic neurologist

    Jerry W. Swanson, M.D.

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Question

Brain lesion: What does it mean?

An MRI revealed that I have a brain lesion, which requires further evaluation. What does the term "lesion" mean? Is it cancer?

Answer

from Jerry W. Swanson, M.D.

A brain lesion is an area of brain tissue that appears abnormal. In the case of an MRI scan, a lesion is an area that doesn't appear normal on the image. However, the meaning of the term "lesion" in this context is unclear.

In some cases, the characteristics of a lesion seen on MRI aren't specific enough to allow the doctor to make a definite diagnosis. When this occurs, additional evaluation may be needed to determine the cause and significance of the lesion.

Potential causes of a brain lesion include:

  • Stroke
  • Cancerous and noncancerous brain tumors
  • Abnormal connection between blood vessels in the brain (arteriovenous malformations)
  • Multiple sclerosis
  • Brain injury
  • Congenital brain anomalies, such as hydrocephalus

AN00973

Nov. 2, 2007

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