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Risk factors
By Mayo Clinic staffFactors that may increase your risk of developing some types of leukemia include:
- Previous cancer treatment. People who've had certain types of chemotherapy and radiation therapy for other cancers have an increased risk of developing certain types of leukemia.
- Genetic diseases. Genetic abnormalities seem to play a role in the development of leukemia. Certain genetic diseases, such as Down syndrome, are associated with increased risk of leukemia.
- Certain blood disorders. People who have been diagnosed with certain blood disorders, such as myelodysplastic syndromes, may have an increased risk of leukemia.
- Exposure to high levels of radiation. People exposed to very high levels of radiation, such as survivors of a nuclear reactor accident, have an increased risk of developing leukemia.
- Exposure to certain chemicals. Exposure to certain chemicals, such as benzene — which is found in gasoline and is used by the chemical industry — also is linked to increased risk of some kinds of leukemia.
- Smoking. Smoking cigarettes increases the risk of acute myelogenous leukemia.
- Family history of leukemia. If members of your family have been diagnosed with leukemia, your risk of the disease may be increased.
However, most people with known risk factors don't get leukemia. And many people with leukemia have none of these risk factors.
References
- What you need to know about leukemia. National Cancer Institute. http://www.cancer.gov/cancertopics/wyntk/leukemia/allpages. Accessed Feb. 17, 2010.
- Leukemia. Leukemia & Lymphoma Society. http://www.leukemia-lymphoma.org/all_page?item_id=7026&viewmode=print. Accessed Feb. 17, 2010.
- SEER stat fact sheets: Acute lymphocytic leukemia. Surveillance Epidemiology and End Results. http://seer.cancer.gov/statfacts/html/alyl.html. Accessed Feb. 23, 2010.
- SEER stat facts sheets: Chronic lymphocytic leukemia. Surveillance Epidemiology and End Results. http://seer.cancer.gov/statfacts/html/clyl.html. Feb. 23, 2010.
- SEER stat facts sheets: Acute myeloid leukemia. Surveillance Epidemiology and End Results. http://seer.cancer.gov/statfacts/html/amyl.html. Feb. 23, 2010.
- SEER stat facts sheets: Chronic myeloid leukemia. Surveillance Epidemiology and End Results. http://seer.cancer.gov/statfacts/html/cmyl.html. Feb. 23, 2010.
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