CausesBy Mayo Clinic staff
The exact cause of lichen sclerosus isn't known. However, the condition may be related to a lack of sex hormones in the affected skin or to an overactive immune system. Previous skin damage at a particular site on your skin may increase the likelihood of lichen sclerosus at that location.
Although lichen sclerosus may involve skin around your genitals, it isn't contagious and cannot spread through sexual intercourse.
Lichen sclerosus occurs most often in postmenopausal women, but it also occurs in men and children. In women, lichen sclerosus usually involves the vulva. In boys and men, uncircumcised males are most at risk, because the condition generally affects the foreskin. In children, the signs and symptoms may improve at puberty.
- Goldsmith LA, et al, eds. Fitzpatrick's Dermatology in General Medicine. 8th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/content.aspx?aID=56040547. Accessed Aug. 28, 2012.
- What is lichen sclerosus? National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Lichen_Sclerosus/default.asp. Accessed Aug. 28, 2012.
- Murphy R. Lichen sclerosus. Dermatology Clinics. 2010;28:707.
- Chi CC, et al. Topical interventions for genital lichen sclerosus. Cochrane Database Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008240.pub2/abstract. Accessed Aug. 28, 2012.
- Wehbe-Alamah H, et al. Silent no more! The lived experiences of women with lichen sclerosis. Journal of the American Academy of Nurse Practitioners. 2012;24:499.