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Livedo reticularis: What causes it?

What causes livedo reticularis? Can it be a sign of an underlying disorder?

- Nancy / Arizona

Mayo Clinic dermatologist Lawrence Gibson, M.D., and colleagues answer select questions from readers.

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Image of livedo reticularis Livedo reticularis

Livedo reticularis is a vascular condition characterized by a purplish mottled discoloration of the skin, usually on the legs. This discoloration is described as lacy or net-like in appearance. Livedo reticularis can be a normal condition that causes no symptoms and needs no treatment. But it can also be associated with a serious underlying disorder, such as lupus, anti-phospholipid syndrome or Sneddon's syndrome. In addition, livedo reticularis may occur as a side effect of certain medications, such as hydroxyurea.

Livedo reticularis may be aggravated by cold exposure. If livedo reticularis is accompanied by pain or discomfort or if ulcers develop in the affected skin, further evaluation may be required. When necessary, treatment depends on the underlying cause, if known, and the severity of symptoms.

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May 17, 2008