Livedo reticularis: When is it a concern?

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    Lawrence E. Gibson, M.D.

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Question

Livedo reticularis: When is it a concern?

What causes livedo reticularis? When should I see a doctor?

Answer

from Lawrence E. Gibson, M.D.

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Image of livedo reticularis
Livedo reticularis

Livedo reticularis is a vascular condition characterized by a purplish discoloration of the skin, usually on the legs. This discoloration is described as lacy or net-like in appearance and may be aggravated by cold exposure.

Most often livedo reticularis causes no symptoms and needs no treatment. But it can be associated with serious underlying disorders, such as lupus, anti-phospholipid syndrome or Sneddon's syndrome. A rare complication of chronic renal dialysis known as calciphylaxis may first present with a livedo reticularis pattern. In addition, livedo reticularis may occur as a side effect of certain medications, such as hydroxyurea (Droxia, Hydrea).

When to see a doctor
See your doctor if:

  • Pain or discomfort accompanies livedo reticularis
  • Ulcers develop in the affected skin

When necessary, treatment depends on the underlying cause, if known, and the severity of symptoms.

References
  1. The skin in immune, autoimmune and rheumatic disorders. In: Wolff K, et al. Fitzpatrick's Color Atlas and Synopsis of Clinical Dermatology. 6th ed. New York, N.Y.: The McGraw-Hill Companies; 2009. http://www.accessmedicine.com/content.aspx?aID=751534. Accessed March 2, 2011.
  2. Hellmann DB, et al. Musculoskeletal & immunologic disorders. In: McPhee SJ, et al. Current Medical Diagnosis & Treatment 2010. 50th ed. New York, N.Y.: The McGraw-Hill Companies; 2011. http://www.accessmedicine.com/content.aspx?aID=10083. Accessed March 2, 2011.
  3. Costner MI, et al. Lupus-nonspecific skin disease. In: Wallace DJ, et al. Dubois' Lupus Erythematosus. 7th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins; 2007.
  4. Gibson LE (expert opinion). Mayo Clinic, Rochester, Minn. April 13, 2011.
  5. Dean SM. Livedo reticularis and related disorders. Current Treatment Options in Cardiovascular Medicine. 2011;2:179.
AN01622 June 16, 2011

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