Acute liver failure

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Symptoms

By Mayo Clinic staff

Signs and symptoms of acute liver failure may include:

  • A yellowing of your skin and eyeballs (jaundice)
  • Tenderness in the upper right area of your abdomen
  • Nausea
  • Vomiting
  • A general sense of not feeling well
  • Difficulty concentrating
  • Disorientation or confusion
  • Sleepiness
  • Muscle tremors

When to see a doctor
Acute liver failure can develop quickly in an otherwise healthy person, and it is life-threatening. If you or someone you know suddenly develops a yellowing of the eyes or skin, tenderness in the upper abdomen or any unusual changes in mental state, personality or behavior, seek medical attention right away.

References
  1. Polson J, et al. AASLD position paper: The management of acute liver failure. Hepatology. 2005;41:1179.
  2. Fontana RJ. Acute liver failure. In: Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2006. http://www.mdconsult.com/das/book/body/135942637-3/0/1389/0.html. Accessed May 7, 2009.
  3. Fontana RJ. Acute liver failure including acetaminophen overdose. The Medical Clinics of North America. 2008;92:761.
  4. Liver health tips. American Association for the Study of Liver Diseases. http://www.aasld.org/yourliver/Pages/LiverHealthTips.aspx. Accessed May 7, 2009.

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July 2, 2009

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