Liver transplant

Free

E-Newsletters

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

What you can expect

By Mayo Clinic staff

CLICK TO ENLARGE

Illustration showing a living-donor liver transplant 
Living liver transplant

During a liver transplant
If you're notified that a liver from a deceased donor is available, you'll be asked to come to the hospital immediately. Your health care team will admit you to the hospital, and you'll undergo an exam to make sure you're healthy enough for the surgery.

Liver transplant surgery is done using general anesthesia, so you'll be unaware during the procedure.

The transplant surgeon makes a long incision across your abdomen to access your liver. The location and size of your incision varies according to your surgeon's approach and your own anatomy.

The surgeon disconnects your liver's blood supply and the bile ducts and then removes the diseased liver. The donor liver is then placed in your body and blood vessels and bile ducts are reattached. Surgery can take up to 12 hours, depending on your situation.

Once your new liver is in place, the surgeon uses stitches and staples to close the surgical incision. You're then taken to the intensive care unit to begin recovery.

Liver transplant using a living donor
If you're receiving a liver transplant from a living donor, such as a friend or family member, surgeons will transplant a portion of the donor's liver in your body. Surgeons first operate on the donor, removing the portion of the liver for transplant. Then surgeons remove your diseased liver and place the donated liver portion in your body. They then connect your blood vessels and bile ducts to the new liver.

The transplanted liver portion in your body and the portion left behind in the donor's body regenerate rapidly.

After a liver transplant
After your liver transplant, you can expect to:

  • Stay in the intensive care unit for a few days. Doctors and nurses will monitor your condition to watch for signs of complications. They'll also test your liver function frequently for signs that your new liver is working.
  • Spend 1 to 2 weeks in the hospital. Once you're stable, you're taken to a transplant recovery area to continue recuperating.
  • Have frequent checkups as you continue recovering at home. Your transplant team designs a checkup schedule for you. You may undergo blood tests a few times each week, at first, and then less often over time.
  • Take medications for the rest of your life. You'll take a number of medications after your liver transplant, many for the rest of your life. Drugs called immunosuppressants help keep your immune system from attacking your new liver. Other drugs help reduce the risk of other complications after your transplant.
References
  1. Martin P, et al. Liver transplantation. In: Feldman M, et al. Sleisinger and Fordtran's Gastrointestinal and Liver Disease. 9th ed. Philadelphia, Pa.: Saunders; 2010. http://www.mdconsult.com/book/player/linkTo?type=bookHome&isbn=978-1-4160-6189-2&eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&uniq=200844987-3. Accessed Oct. 14, 2010.
  2. Liver transplant. American Liver Foundation. http://www.liverfoundation.org/abouttheliver/info/transplant/. Accessed Oct. 14, 2010.
  3. What I need to know about liver transplantation. National Institute for Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/livertransplant_ez/. Accessed Oct. 14, 2010.
  4. Questions & answers for transplant candidates about MELD and PELD. United Network for Organ Sharing. http://www.unos.org/docs/MELD_PELD.pdf. Accessed Oct. 15, 2010.
  5. Liver Kaplan-Meier patient survival rates for transplants performed: 1997-2004. Organ Procurement and Transplantation Network. http://optn.transplant.hrsa.gov/latestData/rptStrat.asp. Accessed Oct. 15, 2010.
MY00349 Dec. 10, 2010

© 1998-2012 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Advertisement


Text Size: smaller largerlarger