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Liver transplant is a treatment option for people who have end-stage liver failure that can't be controlled using other treatments and for some people with liver cancer. Liver failure can occur rapidly, in a matter of weeks (acute liver failure), or it can occur slowly over months and years (chronic liver failure).
Liver failure has many causes, including:
- Liver cirrhosis
- Biliary duct atresia
- Cystic fibrosis
- Early-stage liver cancer
- Hemochromatosis
- Noncancerous (benign) liver tumors
- Primary biliary cirrhosis
- Primary sclerosing cholangitis
- Wilson's disease
Sometimes the cause of liver failure is unknown.
- Rudow DL, et al. Critical care management of the liver transplant recipient. Critical Care Nursing Quarterly. 2008;31:232.
- Liver transplant. American Liver Foundation. http://www.liverfoundation.org/education/info/transplant/. Accessed Oct. 21, 2008.
- What I need to know about liver transplantation. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.nddk.nih.gov/ddiseases/pubs/livertransplant_ez/. Accessed Oct. 21, 2008.
- Koffron A, et al. Liver transplantation: Indications, pretransplant evaluation, surgery, and posttransplant complications. The Medical Clinics of North America. 2008;92:861.
- Arora G, et al. Management of chronic liver failure until liver transplantation. The Medical Clinics of North America. 2008;92:839.
- Brown RS. Live donors in liver transplantation. Gastroenterology. 2008;134:1802.
- O'Leary JG, et al. Indications for liver transplant. Gastroenterology. 2008;134:1764.
- Removal reasons by year. Organ Procurement and Transplantation Network. http://www.optn.org/data/. Accessed Oct. 23, 2008.
- Transplants by donor type. Organ Procurement and Transplantation Network. http://www.optn.org/data/. Accessed Oct. 23, 2008.
- Liver Kaplan-Meier patient survival rates for transplants performed: 1997-2004. Organ Procurement and Transplantation Network. http://www.optn.org/data/. Accessed Oct. 23, 2008.
