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Risk factors
By Mayo Clinic staffYour risk of LCIS may be increased if:
- You have a family history of breast cancer. If one or more close relatives have been diagnosed with breast cancer, you may have an increased risk of LCIS.
- You've taken hormone replacement therapy for menopause. Women who have used hormone replacement therapy to help cope with menopausal signs and symptoms may have an increased risk of LCIS.
- You're a woman in your early 40s. Though LCIS is uncommon, it's most likely to be detected in women in their early 40s who haven't yet experienced menopause. However, LCIS is becoming more common in older women who have undergone menopause.
References
- Abeloff MD, et al. Cancer of the breast. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2008:1875.
- Breast cancer. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/breast.pdf. Accessed April 15, 2011.
- Sabel MS. Lobular carcinoma in situ of the breast. http://www.uptodate.com/home/index.html. Accessed April 26, 2011.
- Venkitaraman R. Lobular neoplasia of the breast. The Breast Journal. 2010;16:519.
- Arpino G ,et al. Premalignant and in situ breast disease: Biology and clinical implications. Annals of Internal Medicine. 2005;143:446.
- SEER stat fact sheet: Breast. National Cancer Institute. http://seer.cancer.gov/statfacts/html/breast.html. Accessed May 4, 2011.
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