Long QT syndrome


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Definition

By Mayo Clinic staff

Long QT syndrome (LQTS) is a heart rhythm disorder that can potentially cause fast, chaotic heartbeats. These rapid heartbeats may trigger a sudden fainting spell or seizure. In some cases, your heart may beat erratically for so long that it can cause sudden death.

You can be born with a genetic mutation that puts you at risk of long QT syndrome. In addition, certain medications and medical conditions may cause long QT syndrome.

Long QT syndrome is treatable. You may need to limit your physical activity, avoid medications known to cause prolonged Q-T intervals or take medications to prevent a chaotic heart rhythm. Some people with long QT syndrome need surgery or an implantable device.

References
  1. Ackerman MJ, et al. Congenital long QT syndrome. In: Gussak I, et al. Electrical Diseases of the Heart; Genetics, Mechanisms, Treatment, Prevention. New York, N.Y.: Springer; 2008:462.
  2. Long QT syndrome. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/qt/qt_whatis.html. Accessed Feb. 10, 2012.
  3. Long QT syndrome. Heart Rhythm Society. http://www.hrsonline.org/PatientInfo/HeartRhythmDisorders/IDisorders/index.cfm. Accessed Feb. 10, 2012.
  4. Madias C, et al. Acquired long QT syndrome from stress cardiomyopathy is associated with ventricular arrhythmias and torsades de pointes. Heart Rhythm. 2011;8:555.
  5. Mauriello DA, et al. Holter monitoring in the evaluation of congenital long QT syndrome. Pacing & Clinical Electrophysiology. 2011;34:1100.
  6. Berul CI, et al. Acquired long QT syndrome. http://www.uptodate.com/index. Accessed March 9, 2012.
  7. Barsheshet A, et al. Genotype-specific QT correction for heart rate and the risk of life-threatening cardiac events in adolescents with congenital long-QT syndrome. Heart Rhythm. 2011;8:1207.
  8. Seslar SP, et al. Diagnosis of congenital long QT syndrome. http://www.uptodate.com/index. Accessed March 9, 2012.
  9. Anand RG, et al. The role of fish oil in arrhythmia prevention. Journal of Cardiopulmonary Rehabilitation and Prevention. 2008;28:92.
  10. Farnsworth MM, et al. When I go in to wake them ... I Wonder: Parental perceptions about congenital long QT syndrome. Journal of the American Academy of Nurse Practitioners. 2006;18:284.
DS00434 April 20, 2012

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