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Risk factors

By Mayo Clinic staff

A number of risk factors are linked to low sperm count and other problems that can cause low sperm count. They include:

  • Being age 35 or older
  • Smoking tobacco
  • Abusing alcohol
  • Using certain illegal drugs
  • Being overweight
  • Being underweight
  • Having certain past or present infections
  • Being exposed to toxins
  • Overheating the testicles
  • Having a prior vasectomy or vasectomy reversal
  • Being born with a fertility disorder or having a blood relative with a fertility disorder
  • Having certain medical conditions, including tumors and chronic illnesses
  • Undergoing medical treatments, such as surgery or radiation for cancer
  • Taking certain medications
  • Bicycling for long periods, especially on a hard seat or poorly adjusted bicycle
References
  1. Guzick DS. Evaluation of the infertile couple. http://www.uptodate.com/home/index.html. Accessed May 7, 2010.
  2. Sigman M, et al. Male infertility. In: Wein AJ, et al. Campbell-Walsh Urology. 9th ed. Philadelphia, Pa.: Saunders; 2007. http://www.mdconsult.com/das/book/body/198188923-5/0/1445/22.html. Accessed May 7, 2010.
  3. Swerdloff  RF, et al. Evaluation of male infertility. http://www.uptodate.com/home/index.html. Accessed May 7, 2010.
  4. Bulun SE, et al. Infertility and subfertility in men. In: Kronenberg HM, et al. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa.: Saunders; 2008. http://www.mdconsult.com/das/book/body/199429868-3/0/1555/120.html?tocnode=54107480&fromURL=120.html#4-u1.0-B978-1-4160-2911-3..50020-0--cesec90_1743. Accessed May 7, 2010.
  5. Swerdloff RF, et al. Causes of male infertility. http://www.uptodate.com/home/index.html. Accessed May 7, 2010.
  6. Leibovitch I, et al. The vicious cycling: Bicycling related urogenital disorders. European Urology. 2005;47:277.
  7. Wang C, et al. Treatment of male infertility. http://www.uptodate.com/home/index.html. Accessed May 7, 2010. Accessed May 10, 2010.
  8. Eskenazi B, et al. Antioxidant intake is associated with semen quality in healthy men. Human Reproduction. 2005;20:1006.
  9. Jurewicz J, et al. Environmental factors and semen quality. International Journal of Occupational Medicine and Environmental Health. 2009;22:305.
  10. Agarwal A, et al. Prevention of oxidative stress injury to sperm. Journal of Andrology. 26;6:2005.
  11. Agarwal A, et al. Carnitines and male infertility. Reproductive BioMedicine Online. 2004;8:376. http://www.rbmonline.com/4DCGI/Article/Detail?38%091%09=%201200%09. Accessed May 7, 2010.
  12. Burns LH. Psychiatric aspects of infertility and infertility treatments. Psychiatric Clinics of North America. 2007;30:689.
  13. Hornstein MD, et al. Optimizing natural fertility in couples planning pregnancy. http://www.uptodate.com/home/index.html. Accessed May 7, 2010.
DS01049 June 11, 2010

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