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  • With Mayo Clinic emeritus internist

    Edward C. Rosenow III, M.D.

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Question

Lung nodules: Can they be cancerous?

Can lung nodules be cancerous?

Answer

from Edward C. Rosenow III, M.D.

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CT scan showing a lung nodule 
Lung nodule

Although most lung nodules are noncancerous (benign), some represent early-stage lung cancer.

Lung nodules — small masses of tissue in the lung — are quite common. They appear as round, white shadows on a chest X-ray or computerized tomography (CT) scan. They're usually about 1/5 inch to 1 inch, or 5 millimeters (mm) to 25 mm, in size. A larger lung nodule, such as one that's 25 mm or larger, is more likely to be cancerous than is a smaller lung nodule.

Your doctor may compare your current chest X-ray or CT scan with a previous one. If the nodule appears in earlier images and hasn't changed in size, shape or appearance, it's probably noncancerous. Causes of noncancerous lung nodules include histoplasmosis, tuberculosis, hematoma, lung cysts and vascular abnormalities. Noncancerous lung nodules usually require no treatment; however, your doctor will probably monitor the nodule for changes using periodic imaging tests.

If a lung nodule is new or has changed in size, shape or appearance, your doctor may recommend further testing — such as a CT scan, positron emission tomography (PET) scan or tissue biopsy — to determine if it is cancerous.

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References
  1. Wahidi MM, et al. Evidence for the treatment of patients with pulmonary nodules: When is it lung cancer? Chest. 2007;132(suppl):94S.
  2. Rosenow EC (expert opinion). Mayo Clinic, Rochester, Minn. April 14, 2009.

AN01082

May 29, 2009

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