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Treatments and drugs
By Mayo Clinic staffAntibiotics are used to treat Lyme disease.
Medications
Oral antibiotics
Oral antibiotics are the standard treatment for early-stage Lyme disease. These usually include doxycycline for adults and children older than 8, or amoxicillin or cefuroxime for adults, younger children, and pregnant or breast-feeding women. These drugs often clear the infection and prevent complications. A 14- to 21-day course of antibiotics is usually recommended, but some studies suggest that courses lasting 10 to 14 days are equally effective.
Intravenous antibiotics
If the disease has progressed, your doctor may recommend treatment with an intravenous antibiotic for 14 to 28 days. This is effective in eliminating infection, although it may take some time to recover symptomatically. Intravenous antibiotics can cause various side effects, including a lower white blood cell count, mild to severe diarrhea, or colonization or infection with other antibiotic resistant organisms unrelated to Lyme.
After treatment, a small number of people still experience some symptoms, such as muscle aches and fatigue. The cause of these continuing symptoms is unknown, but extended antibiotic treatment doesn't make them go away. Some experts believe that certain people who get Lyme disease are predisposed to develop an autoimmune response that contributes to their symptoms. More research is needed.
Avoid Bismacine
The Food and Drug Administration (FDA) warns consumers and health care providers to avoid Bismacine, an injectable compound prescribed by some alternative medicine practitioners to treat Lyme disease. Bismacine, also known as Chromacine, contains high levels of the metal bismuth. Although bismuth is safely used in some oral medications for digestive conditions, it's not approved for use in injectable form or as a treatment for Lyme disease. Bismacine can cause bismuth poisoning, which may lead to heart and kidney failure.
- Hu L. Treatment of Lyme disease. http://www.uptodate.com/home/index.html. Accessed March 24, 2010.
- Hu L. Clinical manifestations of Lyme disease in adults. http://www.uptodate.com/home/index.html. Accessed March 24, 2010.
- Lyme disease. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvbid/lyme/index.htm. Accessed March 24, 2010.
- FDA warns consumers and health care providers not to use bismacine, also known as chromacine. U.S. Food and Drug Administration. http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm150503.htm. Accessed March 29, 2010.
- Wormser GP, et al. The clinical assessment, treatment and prevention of Lyme disease, human granulocytic anaplasmosis and babesiosis: Clinical practice guidelines. Infectious Disease Society of America. 2006;43:1089.
- Lyme disease. National Institute of Allergy and Infectious Diseases. U.S. Department of Health and Human Services. http://www3.niaid.nih.gov/topics/lymeDisease/understanding/. Accessed March 25, 2010.
- Lyme disease: The facts, the challenge. www3.niaid.nih.gov/topics/lymeDisease/PDF/LymeDisease.pdf. Accessed March 29, 2010.
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