Definition
By Mayo Clinic staffApproximately 15 percent of couples are infertile. This means they aren't able to conceive a child even though they've had frequent, unprotected sexual intercourse for a year or longer — or for at least six months if the woman is age 35 or older. In about half of these cases, male infertility plays a role.
Male infertility is due to low sperm production, misshapen or immobile sperm, or blockages that prevent the delivery of sperm. Illnesses, injuries, chronic health problems, lifestyle choices and other factors can play a role in causing male infertility.
Not being able to conceive a child can be stressful and frustrating, but a number of male infertility treatments are available. Approaches can include treatment for the male partner, the female partner, or both.
- Guzick DS. Evaluation of the infertile couple. http://www.uptodate.com/home/index.html. Accessed May 7, 2010.
- Sigman M, et al. Male infertility. In: Wein AJ, et al. Campbell-Walsh Urology. 9th ed. Philadelphia, Pa.: Saunders; 2007. http://www.mdconsult.com/das/book/body/198188923-5/0/1445/22.html. Accessed May 7, 2010.
- Swerdloff RF, et al. Evaluation of male infertility. http://www.uptodate.com/home/index.html. Accessed May 7, 2010.
- Bulun SE, et al. Infertility and subfertility in men. In: Kronenberg HM, et al. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa.: Saunders; 2008. http://www.mdconsult.com/das/book/body/199429868-3/0/1555/120.html?tocnode=54107480&fromURL=120.html#4-u1.0-B978-1-4160-2911-3..50020-0--cesec90_1743. Accessed May 7, 2010.
- Swerdloff RF, et al. Causes of male infertility. http://www.uptodate.com/home/index.html. Accessed May 7, 2010.
- Leibovitch. The vicious cycling: Bicycling related urogenital disorders. European Urology. 2005;47:277.
- Wang C. et al. Treatment of male infertility. http://www.uptodate.com/home/index.html. Accessed May 7, 2010.
- Eskenazi B, et al. Antioxidant intake is associated with semen quality in healthy men. Human Reproduction. 2005;20:1006.
- Jurewicz J, et al. Environmental factors and semen quality. International Journal of Occupational Medicine and Environmental Health. 2009;22:305.
- Agarwal A, et al. Prevention of oxidative stress injury to sperm. Journal of Andrology. 26;6:2005.
- Agarwal A, et al. Carnitines and male infertility. Reproductive BioMedicine Online. 2004;8:376. http://www.rbmonline.com/4DCGI/Article/Detail?38%091%09=%201200%09. Accessed May 7, 2010.
- Burns LH. Psychiatric aspects of infertility and infertility treatments. Psychiatric Clinics of North America. 2007;30:689.
- Hornstein MD, et al. Optimizing natural fertility in couples planning pregnancy. http://www.uptodate.com/home/index.html. Accessed May 7, 2010.

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