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Definition
By Mayo Clinic staffMarfan syndrome is an inherited disorder that affects connective tissue — the fibers that provide the framework and support for your body. As a result, Marfan syndrome can involve many different body systems, including your heart and blood vessels, eyes, and skeleton. The damage caused by Marfan syndrome can be mild or severe. The most serious effects of Marfan syndrome can be life-threatening.
People with Marfan syndrome are usually tall and thin, with disproportionately long arms, legs, fingers and toes. Some experts believe Abraham Lincoln may have had Marfan syndrome. According to the National Institutes of Health, Marfan syndrome occurs in at least one person per 5,000.
