Meniere's disease

Please read: Important 2013 cancer research update from Dr. Michael Camilleri

Free

E-newsletter

Subscribe to Housecall

Our weekly general interest
e-newsletter keeps you up to date on a wide variety of health topics.

Sign up now

Causes

By Mayo Clinic staff

CLICK TO ENLARGE

Illustration showing inner ear and balance 
Inner ear and balance

The cause of Meniere's disease isn't well understood. It appears to be the result of the abnormal volume or composition of fluid in the inner ear.

The inner ear is a cluster of connected passages and cavities called a labyrinth. The outside of the inner ear is made of bone (bony labyrinth). Inside is a soft structure of membrane (membranous labyrinth) that's a slightly smaller, similarly shaped version of the bony labyrinth. The membranous labyrinth contains a fluid (endolymph) and is lined with hair-like sensors that respond to movement of the fluid.

In order for all of the sensors in the inner ear to function properly, the fluid needs to retain a certain volume, pressure and chemical composition. Factors that alter the properties of inner ear fluid may help cause Meniere's disease. Scientists have proposed a number of potential causes or triggers, including:

  • Improper fluid drainage, perhaps because of a blockage or anatomic abnormality
  • Abnormal immune response
  • Allergies
  • Viral infection
  • Genetic predisposition
  • Head trauma
  • Migraines

Because no single cause has been identified, it's likely that Meniere's disease is caused by a combination of factors.

References
  1. Flint PW, et al. Cummings Otolaryngology: Head & Neck Surgery. 5th ed. Philadelphia, Pa.: Mosby Elsevier; 2010. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-323-05283-2..X0001-8--TOP&isbn=978-0-323-05283-2&uniqId=230100505-57. Accessed Aug. 31, 2012.
  2. Meniere's disease. Vestibular DisordersAssociation. http://vestibular.org/menieres-disease. Accessed Aug. 31, 2012.
  3. Dinces EA, et al. Meniere disease. http://www.uptodate.com/index. Accessed Aug. 30, 2012.
  4. Lalwani AK. Current Diagnosis & Treatment in Otolaryngology — Head & Neck Surgery. 3rd ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=39. Accessed Aug. 29, 2012.
  5. Rauch SD. Clinical hints and precipitating factors in patients suffering from Meniere's disease. Otolaryngologic Clinics of North America. 2010;43:1011.
  6. Heart attack, stroke and cardiac arrest warning signs. American Heart Association. http://www.heart.org/HEARTORG/General/Heart-Attack-Stroke-and-Cardiac-Arrest-Signs_UCM_303977_SubHomePage.jsp. Accessed Aug. 31, 2012.
  7. Meniere's disease. American Academy of Otolaryngology — Head and Neck Surgery. http://www.entnet.org/HealthInformation/menieresDisease.cfm. Accessed Aug. 31, 2012.
  8. Meniere's disease. National Institute on Deafness and Other Communication Disorders. http://www.nidcd.nih.gov/health/balance/pages/meniere.aspx. Accessed Aug. 31, 2012.
  9. Potassium. American Cancer Society. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/potassium. Accessed Aug. 31, 2012.
  10. Sodium (salt or sodium chloride). American Heart Association. http://www.heart.org/HEARTORG/GettingHealthy/NutritionCenter/HealthyDietGoals/Sodium-Salt-or-Sodium-Chloride_UCM_303290_Article.jsp. Accessed Aug. 31, 2012.
  11. Neff BA (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 18, 2012.
  12. Neff BA, et al. Auditory and vestibular symptoms and chronic subjective dizziness in patients with Meniere's disease, vestibular migraine, and Meniere's disease with concomitant vestibular migraine. Otology & Neurotology. 2012;33:1235.
DS00535 Dec. 11, 2012

© 1998-2013 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

  • Reprints
  • Print
  • Share on:

  • Email

Advertisement


Text Size: smaller largerlarger