Merkel cell carcinoma

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Causes

By Mayo Clinic staff

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It's not clear what causes Merkel cell carcinoma. Merkel cell carcinoma begins in the Merkel cells. Merkel cells are found at the base of the outermost layer of your skin (epidermis). Merkel cells are connected to the nerve endings in the skin that are responsible for the sense of touch.

References
  1. Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2008. http://www.mdconsult.com/das/book/body/208746819-4/0/1709/0.html. Accessed Oct. 22, 2012.
  2. Merkel cell carcinoma. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed Oct. 22, 2012.
  3. Merkel cell carcinoma treatment (PDQ). National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/merkelcell/patient. Accessed Oct. 22, 2012.
  4. Skin cancer prevention tips. SkinCancerNet. http://www.skincarephysicians.com/skincancernet/prevention.html. Accessed Oct. 22, 2012.
DS00802 Dec. 11, 2012

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