Merkel cell carcinoma

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Causes

By Mayo Clinic staff

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It's not clear what causes Merkel cell carcinoma. Merkel cell carcinoma begins in the Merkel cells. Merkel cells are found at the base of the outermost layer of your skin (epidermis). Merkel cells are connected to the nerve endings in the skin that are responsible for the sense of touch.

References
  1. Wood GS, et al. Nonmelanoma skin cancers: Basal cell and squamous cell carcinomas. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone; 2007:1262.
  2. Merkel cell carcinoma. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/mcc.pdf. Accessed Aug. 23, 2010.
  3. Merkel cell carcinoma treatment (PDQ). National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/merkelcell/patient/allpages. Accessed Aug. 23, 2010.
  4. Skin cancer prevention tips. SkinCancerNet. http://www.skincarephysicians.com/skincancernet/prevention.html. Accessed Aug. 23, 2010.
DS00802 Sept. 11, 2010

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