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Definition

By Mayo Clinic staff

Metabolic syndrome is a cluster of conditions — increased blood pressure, a high blood sugar level, excess body fat around the waist and abnormal cholesterol levels — that occur together, increasing your risk of heart disease, stroke and diabetes.

Having just one of these conditions doesn't mean you have metabolic syndrome. However, any of these conditions increase your risk of serious disease. If more than one of these conditions occur in combination, your risk is even greater.

If you have metabolic syndrome or any of the components of metabolic syndrome, aggressive lifestyle changes can delay or even prevent the development of serious health problems.

Symptoms
References
  1. Alberti KG, et al. Harmonizing the metabolic syndrome: A joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009;120:1640.
  2. Metabolic syndrome. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/ms/ms_all.html. Accessed Jan. 26, 2013.
  3. Ferri FF. Ferri's Clinical Advisor 2013: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-08373-7..00002-9&isbn=978-0-323-08373-7&about=true&uniqId=343863096-23. Accessed Jan. 24, 2013.
  4. Prevention and treatment of metabolic syndrome. American Heart Association. http://www.heart.org/HEARTORG/Conditions/More/MetabolicSyndrome/Prevention-and-Treatment-of-Metabolic-Syndrome_UCM_301927_Article.jsp. Accessed Jan. 24, 2013.
  5. Am I at risk for type 2 diabetes? Taking steps to lower your risk of getting diabetes. National Diabetes Information Clearinghouse. http://diabetes.niddk.nih.gov/dm/pubs/riskfortype2/index.aspx. Accessed Jan. 24, 2013.
  6. Gallagher EJ, et al. The metabolic syndrome - from insulin resistance to obesity and diabetes. Medical Clinics of North America. 2011;95:855.
  7. Meigs JB. The metabolic syndrome (insulin resistance syndrome or syndrome X). http://www.uptodate.com/home. Accessed Jan. 25, 2013.
  8. Spolidoro JV, et al. Waist circumference in children and adolescents correlate with metabolic syndrome and fat deposits in young adults. Clinical Nutrition. 2013;32:93.
DS00522 April 5, 2013

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