Mild cognitive impairment (MCI)

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Complications

By Mayo Clinic staff

People with MCI have a significantly increased risk — but not a certainty — of developing Alzheimer's disease or another type of dementia. Overall, about 1 to 2 percent of older adults develop dementia every year. Among older adults with MCI, studies suggest that 6 to 15 percent develop dementia every year.

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References
  1. McDade EM, et al. Mild cognitive impairment: Epidemiology, pathology, and clinical assessment. http://www.uptodate.com/index. Accessed June 12, 2012.
  2. McDade EM, et al. Mild cognitive impairment: Prognosis and treatment. http://www.uptodate.com/index. Accessed June 12, 2012.
  3. Petersen RC. Mild cognitive impairment. The New England Journal of Medicine. 2011;364:2227.
  4. Shadlen MF, et al. Evaluation of cognitive impairment and dementia. http://www.uptodate.com/index. Accessed June 12, 2012.
  5. Petersen RC, et al. Mild cognitive impairment: Ten years later. Archives of Neurology. 2009;66:1447.
  6. Preventing Alzheimer's disease and cognitive decline. National Institutes of Health State-of-the-Science Conference Statement. April 26-28, 2010. http://consensus.nih.gov/2010/docs/alz/ALZ_Final_Statement.pdf. Accessed June 12, 2012.
  7. Geda YE, et al. Computer activities, physical exercise, aging, and mild cognitive impairment: A population-based study. Mayo Clinic Proceedings. 2012;87:437.
  8. Press D, et al. Prevention of dementia. http://www.uptodate.com/index. Accessed June 12, 2012.
  9. Essentials of a diagnostic work-up. Alzheimer's Association. http://www.alz.org/professionals_and_researchers_14902.asp. June 14, 2012.
  10. What is sleep apnea? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/sleepapnea. Accessed June 14, 2012.
  11. Ahlskog JE, et al. Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging. Mayo Clinic Proceedings. 2011;86:876.
DS00553 Aug. 21, 2012

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