Mild cognitive impairment (MCI)

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Symptoms

By Mayo Clinic staff

Your brain, like the rest of your body, changes as you grow older. Many people notice gradually increasing forgetfulness as they age. It may take longer to think of a word or to recall a person's name.

But consistent or increasing concern about your mental performance may suggest mild cognitive impairment (MCI). Cognitive issues may go beyond what's expected and indicate possible MCI if you experience any or all of the following:

  • You forget things more often.
  • You forget important events such as appointments or social engagements.
  • You lose your train of thought or the thread of conversations, books or movies.
  • You feel increasingly overwhelmed by making decisions, planning steps to accomplish a task or interpreting instructions.
  • You start to have trouble finding your way around familiar environments.
  • You become more impulsive or show increasingly poor judgment.
  • Your family and friends notice any of these changes.

If you have MCI, you may also experience:

  • Depression
  • Irritability and aggression
  • Anxiety
  • Apathy
References
  1. McDade EM, et al. Mild cognitive impairment: Epidemiology, pathology, and clinical assessment. http://www.uptodate.com/index. Accessed June 12, 2012.
  2. McDade EM, et al. Mild cognitive impairment: Prognosis and treatment. http://www.uptodate.com/index. Accessed June 12, 2012.
  3. Petersen RC. Mild cognitive impairment. The New England Journal of Medicine. 2011;364:2227.
  4. Shadlen MF, et al. Evaluation of cognitive impairment and dementia. http://www.uptodate.com/index. Accessed June 12, 2012.
  5. Petersen RC, et al. Mild cognitive impairment: Ten years later. Archives of Neurology. 2009;66:1447.
  6. Preventing Alzheimer's disease and cognitive decline. National Institutes of Health State-of-the-Science Conference Statement. April 26-28, 2010. http://consensus.nih.gov/2010/docs/alz/ALZ_Final_Statement.pdf. Accessed June 12, 2012.
  7. Geda YE, et al. Computer activities, physical exercise, aging, and mild cognitive impairment: A population-based study. Mayo Clinic Proceedings. 2012;87:437.
  8. Press D, et al. Prevention of dementia. http://www.uptodate.com/index. Accessed June 12, 2012.
  9. Essentials of a diagnostic work-up. Alzheimer's Association. http://www.alz.org/professionals_and_researchers_14902.asp. June 14, 2012.
  10. What is sleep apnea? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/sleepapnea. Accessed June 14, 2012.
  11. Ahlskog JE, et al. Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging. Mayo Clinic Proceedings. 2011;86:876.
DS00553 Aug. 21, 2012

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