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Definition
By Mayo Clinic staffMiscarriage is the spontaneous loss of a pregnancy before the 20th week. About 10 to 20 percent of known pregnancies end in miscarriage. But the actual number is probably much higher because many miscarriages occur so early in pregnancy that a woman doesn't even know she's pregnant. Most miscarriages occur because the fetus isn't developing normally.
Miscarriage is a relatively common experience — but that doesn't make it any easier. Ending a pregnancy without a baby to hold in your arms is heartbreaking. Take a step toward emotional healing by understanding what can cause a miscarriage, what increases the risk and what medical care might be needed.
- Tulandi T, et al. Spontaneous abortion: Risk factors, etiology, clinical manifestations, and diagnostic evaluation. http://www.uptodate.com/home/index.html. Accessed Aug. 13, 2008.
- Tulandi T. Patient information: Miscarriage. http://www.uptodate.com/home/index.html. Accessed Aug. 13, 2008.
- Miscarriage. March of Dimes. http://www.marchofdimes.com/printableArticles/681_1192.asp?printable=true. Accessed Aug. 13, 2008.
- Early pregnancy loss: Miscarriage and molar pregnancy. American College of Obstetricians and Gynecologists. http://www.acog.org/publications/patient_education/bp090.cfm. Accessed Aug. 14, 2008.
- Blighted ovum. American Pregnancy Association. http://www.americanpregnancy.org/pregnancycomplications/blightedovum.html. Accessed Aug. 14, 2008.
- Puscheck EE, et al. The impact of male factor on recurrent pregnancy loss. Current Opinions in Obstetrics and Gynecology. 2007;19(3):222-228.
- Tulandi T, et al. Spontaneous abortion: Management. http://www.uptodate.com/home/index.html. Accessed Aug. 13, 2008.
- Cytotec (prescribing information). New York, N.Y.: Pfizer; 2006.
- Cunningham, FG. First-trimester abortion. In: Schorge JO, et al. Williams Gynecology. 1st ed. New York, N.Y.: The McGraw Hill Companies; 2008. http://accessmedicine.com/resourceTOC.aspx?resourceID=514. Accessed Aug. 13, 2008.
- Misoprostol: Drugdex DrugPoint Summary. Micromedex Healthcare Series. http://www.micromedex.com/. Accessed Sept. 19, 2008.
- Sifakis S, et al. High-dose misoprostol used in outpatient management of first trimester spontaneous abortion, Archives of Gynecology and Obstetrics. 2005;272(3):183-186.
- Blum J, et al. Treatment of incomplete abortion and miscarriage with misoprostol. International Journal of Gynecology and Obstetrics. 2007;99(2)(suppl):S186-S189.
- Stephenson M, et al. Evaluation and management of recurrent early pregnancy loss. Clinical Obstetrics and Gynecology. 2007;50(1):132-45.
- Patient's fact sheet: Recurrent pregnancy loss. www.asrm.org/Patients/FactSheets/recurrent_preg_loss.pdf. Accessed Sept. 25, 2008.
