Mitral valve regurgitation

Mayo Clinic Health Manager

Get free personalized health guidance for you and your family.

Get Started

Free

E-Newsletter

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

Risk factors

By Mayo Clinic staff

Several factors can increase your risk of mitral valve regurgitation, including:

  • A history of mitral valve prolapse or mitral valve stenosis. However, having either condition doesn't necessarily mean you'll develop mitral valve regurgitation. In fact, most people with mitral valve prolapse never develop severe regurgitation.
  • A past heart attack. A heart attack can damage your heart, affecting the function of the mitral valve.
  • Use of certain medications. People who take ergotamine and similar medicines for migraines and those who took pergolide (now removed from the market) have an increased risk of mitral regurgitation. Similar problems were noted with the appetite suppressants fenfluramine and dexfenfluramine, which are no longer sold.
  • Infections such as endocarditis or rheumatic fever. Infections can damage the mitral valve.
  • Congenital heart disease. Some people are born with an abnormal mitral valve prone to regurgitation. Often babies born with heart defects may have more than one problem, such as a hole in the upper chambers of the heart (atrial septal defect) and an abnormal mitral valve.
  • Age. By middle age, many people have some mitral valve regurgitation caused by natural deterioration of the valve. However, mitral valve regurgitation causes symptoms in only a small percentage of older adults.
References
  1. Gaasch WH. Overview of the management of chronic mitral regurgitation. http://www.uptodate.com/home/index.html. Accessed July 14, 2009.
  2. Otto CM. Etiology, clinical features, and evaluation of chronic mitral regurgitation. http://www.uptodate.com/home/index.html. Accessed July 14, 2009.
  3. Heart valves. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=4598. Accessed July 14, 2009.
  4. Nishimura RA. ACC/AHA guideline update on valvular heart disease: Focused update on infective endocarditis. Circulation. 2008;118:887.
  5. Bonow RO, et al. ACC/AHA 2006 Guidelines for the management of patients with valvular heart disease: Executive summary a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2006;114:450.
  6. Gaasch WH. Indications for and types of corrective surgery in severe chronic mitral valve regurgitation. http://www.uptodate.com/home/index.html. Accessed July 14, 2009.

DS00421

Sept. 18, 2009

© 1998-2009 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Reliable tools for healthier lives," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Text Size: smaller largerlarger