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Symptoms
By Mayo Clinic staffMixed connective tissue disease doesn't have a unique set of signs and symptoms. Instead, people with mixed connective tissue disease usually have signs and symptoms of lupus, scleroderma and polymyositis, including:
- Fatigue
- Muscle weakness
- Joint pain
- Joint swelling
- Swollen fingers
- Mild fever
- Raynaud's phenomenon — blood vessel spasms that interrupt blood flow to the fingers, toes, ears and nose
