Mixed connective tissue disease

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Tests and diagnosis

By Mayo Clinic staff

Your doctor may suspect mixed connective tissue disease based on your signs and symptoms. A physical exam may reveal signs such as swollen hands and painful, swollen joints. A blood test can determine whether you have a certain antibody in your blood that indicates mixed connective tissue disease.

References
  1. Firestein GS, et al. Kelley's Textbook of Rheumatology. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2009. http://www.mdconsult.com/das/book/body/208746819-6/0/1807/0.html. Accessed March 23, 2012.
  2. Ortega-Hernandez OD, et al. Mixed connective tissue disease: An overview of clinical manifestations, diagnosis and treatment. Best Practice & Research Clinical Rheumatology. 2012;26:61.
  3. Bennett RM. Clinical manifestations of mixed connective tissue disease. http://www.uptodate.com/index.html. Accessed March 23, 2012.
  4. Mixed connective tissue disease. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/musculoskeletal_and_connective_tissue_disorders/autoimmune_rheumatic_disorders/mixed_connective_tissue_disease_mctd.html?qt=mixed connective&alt=sh. Accessed March 23, 2012.
  5. Saag KG, et al. Major side effects of systemic glucocorticoids. http://www.uptodate.com/index.html. Accessed March 23, 2012.
  6. Ferri FF. Ferri's Clinical Advisor 2012: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-323-05611-3..C2009-0-38601-8--TOP&isbn=978-0-323-05611-3&uniqId=291436269-101. Accessed March 23, 2012.
  7. Bennett RM. Prognosis and treatment of mixed connective tissue disease. http://www.uptodate.com/index.html. Accessed March 23, 2012.
DS00675 May 30, 2012

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