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Risk factors

By Mayo Clinic staff

Molar pregnancy is uncommon, occurring in about 1 in every 1,000 pregnancies. Various factors are associated with molar pregnancy, including:

  • Maternal age. A molar pregnancy is more likely for a woman older than age 35 or younger than age 20.
  • Previous molar pregnancy. If you've had one molar pregnancy, you're more likely to have another. A repeat molar pregnancy happens, on average, in 1 to 2 out of every 100 women.
  • Some ethnic groups. Women of Southeast Asian descent appear to have a higher risk of molar pregnancy.
References
  1. Early pregnancy loss: Miscarriage and molar pregnancy. American College of Obstetricians and Gynecologists. http://www.acog.org/publications/faq/faq090.cfm. Accessed Sept. 29, 2011.
  2. Ectopic and molar pregnancy. March of Dimes. http://www.marchofdimes.com/Baby/loss_ectopic.html. Accessed Oct. 3, 2011.
  3. Copeland LJ, et al. Malignant diseases and pregnancy. In: Gabbe SG, et al. Obstetrics: Normal and Problem Pregnancies. 5th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2007. http://www.mdconsult.com/das/book/body/208746819-4/0/1528/0.html. Accessed Oct. 3, 2011.
  4. Garner EIO. Gestational trophoblastic disease: Management of hydatidiform mole. http://www.uptodate.com/home/index.html. Accessed Sept. 29, 2011.
  5. Kindelberger DW, et al. Gestational trophoblastic disease: Pathology. http://www.uptodate.com/home/index.html. Accessed Sept. 29, 2011.
  6. Chiang JW, et al. Gestational trophoblastic disease: Epidemiology, clinical manifestations and diagnosis. http://www.uptodate.com/home/index.html. Accessed Sept. 29, 2011.
  7. Garner EIO. Malignant gestational trophoblastic disease: Staging and treatment. http://www.uptodate.com/home/index.html. Accessed Sept. 29, 2011.
  8. Kavanagh JJ, et al. Gestational trophoblastic disease: Hydatidiform mole, nonmetastatic and metastatic gestational trophoblastic tumor: Diagnosis and management. In: Katz VL, et al. Comprehensive Gynecology. 5th ed. Philadelphia, Pa.: Mosby Elsevier; 2007. http://www.mdconsult.com/das/book/body/208746819-4/0/1524/0.html. Accessed Oct. 5, 2011.
  9. Dilation and curettage. American College of Obstetricians and Gynecologists. http://www.acog.org/publications/faq/faq062.cfm. Accessed Oct. 5, 2011.
  10. Al-Hussaini TK, et al. Recurrent pregnancy loss due to familial and non-familial habitual molar pregnancy. International Journal of Gynecology and Obstetrics. 2003;83:179.
  11. Soper JT, et al. Diagnosis and treatment of gestational trophoblastic disease: ACOG practice bulletin No. 53. Gynecologic Oncology. 2004;93:575.
  12. Harms RW (expert opinion). Mayo Clinic, Rochester, Minn. Oct. 9, 2011.
DS01155 Nov. 11, 2011

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