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Risk factors

By Mayo Clinic staff

Several types of moles have a higher than average risk of becoming cancerous. They include:

  • Large moles present at birth. Large moles that are present at birth are called congenital nevi or giant hairy nevi. These moles may increase your risk of malignant melanoma, a deadly form of skin cancer. In general, moles that are more than the size of a closed fist pose the greatest risk. Have your doctor examine any mole that was present at birth and is fist-sized or larger.
  • Moles that run in families. Moles that are larger than average — which is about 1/4 inch (6 millimeters), or the diameter of a pencil eraser — and irregular in shape are known as atypical (dysplastic) nevi. These moles tend to be hereditary. They're frequently described as looking like fried eggs because they usually have dark brown centers and lighter, uneven borders. Overall, they may look red or tan. If you have dysplastic nevi, you have a greater risk of developing malignant melanoma.
  • Numerous moles. If you have many moles — 50 or more — you are at a greater risk of developing melanoma.

DS00121

Feb. 19, 2008

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