Risk factors
By Mayo Clinic staffFactors that increase your risk of monoclonal gammopathy of undetermined significance include:
- Your age. The risk of monoclonal gammopathy of undetermined significance increases as you get older. The highest incidence is among adults age 85 and older.
- Your race. Blacks are more likely to experience this condition than are whites.
- Your sex. Monoclonal gammopathy of undetermined significance is more common in men than it is in women.
- A family history. If other people in your family have monoclonal gammopathy of undetermined significance, your risk of developing the disorder may be higher.
References
- Rajkumar SV. Diagnosis of monoclonal gammopathy of undetermined significance. http://www.uptodate.com/home. Accessed April 3, 2013.
- Rajkumar SV. Clinical course and management of monoclonal gammopathy of undetermined significance. http://www.uptodate.com/home. Accessed April 3, 2013.
- Blade J. Monoclonal gammopathies of undetermined significance. New England Journal of Medicine. 2006;355:2765.
- Rajkumar SV, et al. Advances in the diagnosis, classification, risk stratification, and management of monoclonal gammopathy of undetermined significance: Implications for recategorizing disease entities in the presence of evolving scientific evidence. Mayo Clinic Proceedings. 2010;85:945.
- Therneau TM. Incidence of monoclonal gammopathy of undetermined significance and estimation of duration before first clinical recognition. Mayo Clinic Proceedings. 2012;87:1071.


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