
- With Mayo Clinic internist
James M. Steckelberg, M.D.
read biographyclose windowBiography of
James M. Steckelberg, M.D.
James Steckelberg, M.D.
Dr. James Steckelberg is a consultant in the Division of Infectious Diseases and a professor of medicine at Mayo Medical School.
A native of Fremont, Neb., Dr. Steckelberg was a Rhodes Scholar and graduated from the Mayo Graduate School of Medicine as a resident in internal medicine and a fellow in infectious diseases, and is board certified in both. He is the former director of the Infectious Diseases Research Laboratory at Mayo Clinic.
Dr. Steckelberg belongs to numerous professional organizations. He is a founding member of the Musculoskeletal Infection Society and a fellow of the American College of Physicians and of the Infectious Diseases Society of America. He has served on many Mayo Clinic committees and is a member of the Department of Medicine Leadership Committee and of the executive committee of the Division of Infectious Diseases. He also served on the editorial boards of "Mayo Clinic Proceedings" and "Antimicrobial Agents and Chemotherapy" and has been an editorial reviewer for more than a dozen publications.
Dr. Steckelberg's research interests include experimental models of infection, epidemiology of infection, and antimicrobial resistance and therapy of bacterial infections.
Complications (1)
- Mononucleosis: Can it recur?
Question
Mononucleosis and Epstein-Barr: What's the connection?
What's the connection between mononucleosis and Epstein-Barr virus?
Answer
from James M. Steckelberg, M.D.
Epstein-Barr virus (EBV), a widespread human herpes virus, can cause mononucleosis — but usually, it doesn't. In fact, most EBV infections aren't noticeable, even when they're most active in your body. By age 35, almost everyone has antibodies to EBV, indicating past infection.
It takes more than an uncovered cough or sneeze to transmit EBV. During primary infection, people shed the virus in saliva. You need close contact, such as kissing or sharing a cup with an infected person, to catch EBV.
The infection generally causes no signs or symptoms, except in teenagers and young adults. In that age group, up to half of EBV infections cause mononucleosis — a disease that features fatigue, headache, fever, sore throat and swollen lymph nodes.
Next questionMononucleosis: Can it recur?
- Epstein-Barr virus and infectious mononucleosis. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/diseases/ebv.htm. Accessed Sept. 20, 2011.
- Sullivan JL. Clinical manifestations and treatment of Epstein-Barr virus. http://www.uptodate.com/home/index.html. Accessed Sept. 20, 2011.


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