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Alternative medicine

By Mayo Clinic staff

Para-aminobenzoic acid (PABA) is an oral medication that has been used to treat morphea and scleroderma. However, it hasn't been proved to reduce skin symptoms in clinical trials. If you're interested in trying PABA, discuss its proper use with your doctor.

Coping and support Lifestyle and home remedies
References
  1. Falanga V, et al. Morphea. In: Wolff K, et al. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York, N.Y.: McGraw-Hill Medical; 2003. http://www.accessmedicine.com/content.aspx?aID=2968193. Accessed March 25, 2010.
  2. Localized scleroderma. In: Habif TP. Clinical Dermatology. 5th ed. Maryland Heights, Mo.: Mosby Elsevier; 2010. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-0-7234-3541-9..00026-2--s0690&displayedEid=4-u1.0-B978-0-7234-3541-9..00026-2--s0695&uniq=191199955&isbn=978-0-7234-3541-9&sid=973634049. Accessed March 25, 2010.
  3. Scleroderma. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Scleroderma/default.asp. Accessed March 25, 2010.
  4. Localized scleroderma. Scleroderma Foundation. http://www.scleroderma.org/pdf/Medical_Brochures/Localized.pdf. Accessed March 25, 2010.
  5. Dovonex (prescribing information). Dublin, Ireland: Leo Laboratories; 2007. http://www.accessdata.fda.gov/drugsatfda_docs/label/2007/020611s007,020554s007,020273s009lbl.pdf. Accessed March 25, 2010.
  6. Prednisone. Micromedex Healthcare Series. http://www.micromedex.com. Accessed March 26, 2010.
  7. Franks AG. Skin manifestations of internal disease. Medical Clinics of North America. 2009;93:1265.
  8. Plaquenil (prescribing information). Bridgewater, N.J.: Sanofi-Aventis; 2006. http://www.accessdata.fda.gov/drugsatfda_docs/label/2007/009768s041lbl.pdf. Accessed March 25, 2010.
  9. Neoral (prescribing information). East Hanover, N.J.: Novartis; 2009. http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/050715s028,050716s029lbl.pdf. Accessed March 25, 2010.
  10. Methotrexate (prescribing information). Fort Lee, N.J.: Dava Pharmaceuticals; 2009. http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/008085s063lbl.pdf. Accessed March 25, 2010.
  11. Yancey KB, et al. Immunologically mediated skin diseases. In: Fauci AS, et al. Harrison's Principles of Internal Medicine. 17th ed. New York, N.Y.: McGraw-Hill Medical; 2008. http://www.accessmedicine.com/content.aspx?aID=2868360. Accessed March 25, 2010.
  12. Para-aminobenzoic acid (PABA). Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed March 25, 2010.
  13. Gibson LE (expert opinion). Mayo Clinic, Rochester, Minn. March 30, 2010.
DS00718 May 6, 2010

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