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Complications

By Mayo Clinic staff

Morphea can cause a number of complications, including:

  • Self-esteem issues. Morphea can have a negative effect on your self-esteem and body image, particularly if discolored patches of skin appear on your arms, legs or face.
  • Movement problems. Morphea that affects the arms and legs can impair joint mobility.
  • Widespread areas of hardened, discolored skin. Numerous new patches of hard, discolored skin may seem to join together, a condition known as generalized morphea.
References
  1. Wolff K, et al. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York, N.Y.: The McGraw-Hill Companies; 2008. http://www.accessmedicine.com/content.aspx?aID=2968193. Accessed Aug. 7, 2012.
  2. Habif TP. Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 5th ed. Edinburgh, U.K.; New York, N.Y.: Mosby Elsevier; 2010. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-7234-3541-9..X0001-6--TOP&isbn=978-0-7234-3541-9&uniqId=230100505-57. Accessed Aug. 7, 2012.
  3. Scleroderma. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Scleroderma/default.asp. Accessed Aug. 7, 2012.
  4. Localized scleroderma. Scleroderma Foundation. http://www.scleroderma.org/pdf/Medical_Brochures/Localized.pdf. Accessed Aug. 7, 2012.
  5. Badea I, et al. Pathogenesis and therapeutic approaches for improved topical treatment in localized scleroderma and systemic sclerosis. Rheumatology. 2009;48:213.
  6. Morphea. National Institutes of Health. http://rarediseases.info.nih.gov/GARD/Condition/10485/Morphea.aspx. Accessed Aug. 7, 2012.
  7. Valanclene G, et al. Pathogenesis and treatment modalities of localized scleroderma. Medicina (Kaunas). 2010;46:649.
  8. Fett NM. Morphea: Evidence-based recommendations for treatment. Indian Journal of Dermatology, Venereology and Leprology. 2012;78:135.
  9. Zancanaro PCQ, et al. Localized scleroderma in children: Clinical, diagnostic and therapeutic aspects. Anais Brasileiros de Dermatologia. 2009;84:1.
  10. Mild psoriasis: Non-steroidal prescription topical treatments. National Psoriasis Foundation. http://www.psoriasis.org/about-psoriasis/treatments/topicals/non-steroid. Accessed Aug. 7, 2012.
  11. Prednisone. PubMed Health. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000091/. Accessed Aug. 7, 2012.
  12. Plaquenil (prescribing information). Bridgewater, N.J.: Sanofi-Aventis; 2006. http://www.accessdata.fda.gov/drugsatfda_docs/label/2007/009768s041lbl.pdf. Accessed Aug. 7, 2012.
  13. Neoral (prescribing information). East Hanover, N.J.: Novartis; 2009. http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/050715s028,050716s029lbl.pdf. Accessed Aug. 7, 2012.
  14. Methotrexate (Rheumatrex, Trexall). American College of Rheumatology. http://www.rheumatology.org/practice/clinical/patients/medications/methotrexate.asp. Accessed Aug. 7, 2012.
  15. Para-aminobenzoic acid (PABA). Natural Medicines Comprehensive Database. http://naturaldatabase.therapeuticresearch.com/nd/PrintVersion.aspx?cs=MAYO&s=ND. Accessed Aug. 7, 2012.
DS00718 Oct. 5, 2012

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